Reversed-phase high-performance liquid chromatography of 4-(2-pyridyl)-1-piperazinethiocarboxylic acid 2-[1-(pyridyl)ethylidene]hydrazide dihydrochloride (NSC 348977), a synthetic thiosemicarbazone with antitumor activity

Selenium dioxide catalysed oxidation of acetic acid hydrazide by bromate in aqueous hydrochloric acid medium

“…2 They also form coordination complexes with many transition metal ions which make them good reagents for metal extraction, polymer stabilization and ion exchange problems. [3][4][5][6][7] These hydrazides act as bidentate ligands involving carbonyl oxygen and the nitrogen 2 of the amino group of the hydrazine moiety with the metal ions. These hydrazides also exhibit carcinostatic, antibacterial and antifungal properties 2 and complexation with metal ions is reported to enhance 8 their biological activity.…”

Kinetic parameters and thermal decomposition for Novel 1,1-Malonyl-bis(4-p-Chlorophenylthiosemicarbazide) and Cu(II), Co(II), Zn(II) and Sn(II) complexes(H<sub>4</sub>pClMaTS) synthesized by electrochemical method

“…Thiosemicarbazide and their derivatives are of current interest with respect to their uses as analytical reagents for high performance liquid chromatographic separations of metal(II) ions as metal chelates [1][2][3], potentiometric sensors [4], analytical detrmenation of metal ions [5] and clinical analysis [6]. Most of these compounds have antifungal [7], antimicrobial [8], antitumor [9], biological activity [10,11] as well as hypoglycemic effects [12][13][14].…”