Reversibility of disturbed pituitary function in pediatric conditions with psychological stressors: implications for clinical practice

Giannakopoulos, Aristeidis; Chrysis, Dionisios

doi:10.1007/s42000-024-00536-z

Hormones

2024

DOI: 10.1007/s42000-024-00536-z

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Reversibility of disturbed pituitary function in pediatric conditions with psychological stressors: implications for clinical practice

Aristeidis Giannakopoulos,

Dionisios Chrysis

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2024

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Cited by 2 publications

References 83 publications

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Molecular genetics of adrenal Cushing’s syndrome, a Menelaos Batrinos Scholar’s review, and the principle of gutta cavat lapidem in research

Stratakis

2024

Hormones

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Molecular genetics of adrenal Cushing’s syndrome, a Menelaos Batrinos Scholar’s review, and the principle of gutta cavat lapidem in research

Stratakis

2024

Hormones

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Disorders of puberty and neurodevelopment: A shared etiology?

Read,

Vasile‐Tudorache,

Newsome

et al. 2024

Annals of the New York Academy of Sciences

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The neuroendocrine control of puberty and reproduction is fascinatingly complex, with up‐ and down‐regulation of key reproductive hormones during fetal, infantile, and later childhood periods that determine the correct function of the hypothalamic–pituitary–gonadal axis and the timing of puberty. Neuronal development is a vital element of these processes, and multiple conditions of disordered puberty and reproduction have their etiology in abnormal neuronal migration or function. Although there are numerous documented cases across multiple conditions wherein patients have both neurodevelopmental disorders and pubertal abnormalities, this has mostly been described ad hoc and the associations are not clearly documented. In this review, we aim to describe the overlap between these two groups of conditions and to increase awareness to ensure that puberty and reproductive function are carefully monitored in patients with neurodevelopmental conditions, and vice versa. Moreover, this commonality can be explored for clues about the disease mechanisms in these patient groups and provide new avenues for therapeutic interventions for affected individuals.

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Reversibility of disturbed pituitary function in pediatric conditions with psychological stressors: implications for clinical practice

Cited by 2 publications

References 83 publications

Molecular genetics of adrenal Cushing’s syndrome, a Menelaos Batrinos Scholar’s review, and the principle of gutta cavat lapidem in research

Molecular genetics of adrenal Cushing’s syndrome, a Menelaos Batrinos Scholar’s review, and the principle of gutta cavat lapidem in research

Disorders of puberty and neurodevelopment: A shared etiology?

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