Reversible Bronchiectasis in an Adult

Yap, Vanessa; Metersky, Mark L.

doi:10.1097/lbr.0b013e31826ca79d

Cited by 13 publications

(12 citation statements)

References 4 publications

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“…Bronchiectasis is generally defined as an irreversible widening of the airway. The reversibility of radiological bronchiectasis has been discussed in a number of case reports [42,43], and in a few small retrospective studies including both adult and paediatric patients [44][45][46][47]. A few critical notes are needed.…”

Section: Reversibility Of Bronchiectasismentioning

confidence: 99%

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The radiological diagnosis of bronchiectasis: what's in a name?

et al. 2020

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Diagnosis of bronchiectasis is usually made using chest computed tomography (CT) scan, the current gold standard method. A bronchiectatic airway can show abnormal widening and thickening of its airway wall. In addition, it can show an irregular wall and lack of tapering, and/or can be visible in the periphery of the lung. Its diagnosis is still largely expert based. More recently, it has become clear that airway dimensions on CT and therefore the diagnosis of bronchiectasis are highly dependent on lung volume. Hence, control of lung volume is required during CT acquisition to standardise the evaluation of airways. Automated image analysis systems are in development for the objective analysis of airway dimensions and for the diagnosis of bronchiectasis. To use these systems, clear and objective definitions for the diagnosis of bronchiectasis are needed. Furthermore, the use of these systems requires standardisation of CT protocols and of lung volume during chest CT acquisition. In addition, sex- and age-specific reference values are needed for image analysis outcome parameters. This review focusses on today's issues relating to the radiological diagnosis of bronchiectasis using state-of-the-art CT imaging techniques.

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Section: Reversibility Of Bronchiectasismentioning

confidence: 99%

“…A few critical notes are needed. In some of these papers [43], the methodology of both image acquisition and analysis are not well defined. This is highly relevant, as a volumetric CT protocol is required to allow a slice by slice comparison at identical anatomical levels between the baseline scan and the follow-up scan.…”

Section: Reversibility Of Bronchiectasismentioning

confidence: 99%

The radiological diagnosis of bronchiectasis: what's in a name?

et al. 2020

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“…1,2 Bronchiectasis can develop as a result of different airway insults and is a chronic infective and inflammatory respiratory disease that causes significant morbidity and mortality. [3][4][5][6] Bronchiectasis may cause pulmonary infections and loss of lung function.…”

Section: Introductionmentioning

confidence: 99%

Low Cognitive Ability in Subjects With Bronchiectasis

Gülhan¹,

Bulcun²,

Gülhan

et al. 2015

Respir Care

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BACKGROUND: Bronchiectasis may change cognitive function. The mechanism responsible for cognitive dysfunction in COPD may be neuronal damage caused by hypoxia. Cognitive function in patients with bronchiectasis is also likely to be affected by similar mechanisms. The goal of this study was to determine the frequency and determinants of low cognitive ability in subjects with stable bronchiectasis. METHODS: Thirty subjects with stable bronchiectasis and 25 healthy volunteers underwent a cognitive ability assessment using the Wechsler Adult Intelligence Scale. Bronchiectasis was diagnosed by high-resolution computed tomography of the chest. Age, body mass index, the Hospital Anxiety and Depression Scale, and pulmonary function were assessed. Perceived intensity of dyspnea after exercise (after climbing 3 flights of stairs) was estimated using a modified Borg scale. RESULTS: Mean scores on the verbal and performance tests and full-scale IQ scores were significantly lower in subjects with bronchiectasis than in healthy volunteers. Low cognitive ability in subjects with bronchiectasis was associated with higher depression scores, lower oxygen saturation, and poor lung function after adjusting for potential confounders in multivariate analysis. Borg scores after exercise in subjects with bronchiectasis and low cognitive ability were higher than those in subjects with bronchiectasis and high cognitive ability, despite similar P aO 2 and FEV 1 in both groups. CONCLUSIONS: Low cognitive ability in subjects with bronchiectasis may be associated with reduced lung function, more serious hypoxemia, and higher depressive symptoms. Subjects with bronchiectasis and low cognitive ability feel more intense dyspnea than do those with high cognitive ability.

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“…[ 2 ] Diagnosis has been greatly facilitated by high-resolution computed tomography (HRCT). [ 1 , 2 ] There had been several case reports [ 4 – 6 ] of complete disappearance of bronchial dilatation in adults demonstrated by bronchography 50 years ago and a case report [ 7 ] as evidenced by HRCT 5 years ago.…”

Section: Introductionmentioning

confidence: 99%

Could Chinese herbs accelerate the resolution of reversible bronchiectasis in adults?

Guo²

2017

Medicine

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Rationale:The classic definition of bronchiectasis is of permanent bronchial dilatation. Therefore, bronchiectasis is generally considered irreversible in the adult population.Patient concerns:A 27-year-old woman presented to an affiliated hospital with a 1-year history of productive cough.Diagnosis:Bronchiectasis.Interventions:The patient was treated with cephalosporin and a mucus clearance regimen for 6 days and then with Chinese herbs for 3 months.Outcomes:Reversible bronchial dilatation was evidenced by sequential chest high-resolution computed tomography 6 months later.Conclusion:The current report demonstrated that, although rare in adult, bronchial dilatation might resolve completely in such a short period if receiving adequate regimens, for example, Chinese herbs.

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Reversible Bronchiectasis in an Adult

Cited by 13 publications

References 4 publications

The radiological diagnosis of bronchiectasis: what's in a name?

The radiological diagnosis of bronchiectasis: what's in a name?

Low Cognitive Ability in Subjects With Bronchiectasis

Could Chinese herbs accelerate the resolution of reversible bronchiectasis in adults?

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