Reversible Dementias

Philpot, Michael

doi:10.1002/9780470669600.ch61

Cited by 1 publication

(1 citation statement)

References 70 publications

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“…[33][34][35][36] Health care professionals sometimes need to remember to consider B12 deficiency in the differential diagnosis, resulting in prolonged investigations and misdiagnosis. [37][38][39][40][41][42][43] Failure to use and inaccessibility of second-line tests, such as the metabolites MMA and homocysteine. These tests are essential in diagnosing B12 deficiency when blood levels of B12 are lownormal to normal.…”

Section: Delay In Diagnosis and Treatmentmentioning

confidence: 99%

Lack of Clinical Evidence Regarding the Guidelines for Vitamin B12 Deficiency: An Analysis From Literature and Recommendations From Clinical Practice

Plattel

2024

Food Nutr Bull

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Background: Vitamin B12 deficiency is a critical medical condition that, if left untreated, can lead to severe symptoms and potentially serious and life-threatening complications. Clinical guidelines are designed to provide a standardized approach to diagnosis and treatment, aiming for consistency and effectiveness. However, it is well-established that not all patients fit into general guidelines. Objective: To investigate the clinical relevance of the submitted research to support these protocols for diagnosing and treating a B12 deficiency. Approach: Conducting a literature review of the references focused and used on diagnosing and treating vitamin B12 deficiency in adults and children. Results: No robust clinical trial nor RCT has been found to back up the current protocols. The research used is primarily based on assumptions rather than solid clinical evidence. Conclusion: Existing guidelines for vitamin B12 deficiency need to be significantly revised and improved through clinical research, clinical experience by experts in the field with input from patient groups worldwide.

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Section: Delay In Diagnosis and Treatmentmentioning

confidence: 99%

Lack of Clinical Evidence Regarding the Guidelines for Vitamin B12 Deficiency: An Analysis From Literature and Recommendations From Clinical Practice

Plattel

2024

Food Nutr Bull

View full text Add to dashboard Cite

show abstract

Reversible Dementias

Cited by 1 publication

References 70 publications

Lack of Clinical Evidence Regarding the Guidelines for Vitamin B12 Deficiency: An Analysis From Literature and Recommendations From Clinical Practice

Lack of Clinical Evidence Regarding the Guidelines for Vitamin B12 Deficiency: An Analysis From Literature and Recommendations From Clinical Practice

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