Reversible Distension of the Subarachnoid Space around the Optic Nerves in a Case of Idiopathic Hypertrophic Pachymeningitis

Hiraka, Toshitada; Koyama, Shingo; Kurokawa, K; Tanji, Haruko; Iseki, Chifumi; Wada, Manabu; Kawanami, Toru; Oda, Atsuko; Hosoya, Takamitsu; Kato, Takeshi

doi:10.2463/mrms.11.141

Cited by 6 publications

(2 citation statements)

References 10 publications

(18 reference statements)

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“…Nosotros sostenemos que el espectro de alteraciones de presión intracraneal en una misma enfermedad se podría relacionar con una alteración en la fluídica del líquido cefalorraquídeo. Se ha descrito, mediante resonancia nuclear magnética, que existe una distensión del espacio subaracnoideo perióptico debido a una obstrucción entre el nervio óptico y la cisterna quiasmática (Hiraka et al, 2012). Nosotros creemos que los cambios adicionales en flujos de líquido cerebro espinal podrían estar ocurriendo y podrían ser en parte responsables de la variabilidad de la presión intracraneal.…”

Section: Discussionunclassified

Paquimeningitis relacionada con IgG4 y la visión. Reporte de caso

Jalil

Alarcón

Salazar

et al. 2020

ARS med

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Se presenta el caso de una mujer de 51 años que consulta por disminución de agudeza visual, escotoma central en ojo izquierdo y edema de papila bilateral. Se encuentran signos compatibles con paquimeningitis en la resonancia nuclear magnética. También presenta aumento de presión de apertura en la punción lumbar. En el estudio de laboratorio se observa un aumento en los niveles plasmáticos de IgG4, lo cual llevó al diagóstico de paquimeningitis relacionada con IgG4. La paciente fue tratada con corticoides y azatioprina, con excelente evolución posterior al normalizar agudeza visual y campos visuales. En este artículo se describen tres elementos importantes a considerar en estos pacientes: pérdida de visión, edema de discos ópticos y cambios en campo visual.

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Section: Discussionunclassified

Paquimeningitis relacionada con IgG4 y la visión. Reporte de caso

Jalil

Alarcón

Salazar

et al. 2020

ARS med

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“…The “tram‐track” sign and the “donut configuration” are thought to indicate an increased volume of cerebrospinal fluid around the optic nerve sheaths reflecting the compression in the proximal side of the optic nerve, intracranial hypertension, optic neuritis and hypertrophic pachymeningitis . In the present case, the histopathological study showed that there was no abnormal tissue around the orbital portion of the bilateral optic nerves, while Aspergillus was found around the optic chiasm.…”

Section: Discussionmentioning

confidence: 99%

An autopsy case of invasive sino‐orbital aspergillosis presenting the “tram‐track” sign and “donut configuration” in the orbital magnetic resonance imaging

Morimoto

Takahashi

et al. 2016

Neurology & Clinical Neurosc

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An 84-year-old man with diabetes mellitus presented with a right orbital apex syndrome. In the orbital magnetic resonance imaging, the fat-suppressed T2-weighted image showed a hyperintense parallel linear lesion on the right optic nerve and a ring lesion around it, producing the "tram-track" sign on the axial view and the "donut configuration" on the coronal view. A trans-sphenoid endoscopic orbital biopsy showed an infection of Aspergillus fumigatus. Despite treatment with oral voriconazole, the patient died from deterioration of chronic heart failure. An autopsy found normal tissue around the orbital portion of bilateral optic nerves, while Aspergillus was found around the optic chiasm. The "tram-track" sign and the "donut configuration" in the orbital magnetic resonance imaging were beneficial for the diagnosis of invasive sino-orbital aspergillosis.

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Neuro-ophthalmologic Complications of Neoplastic Leptomeningeal Disease

Szatmáry

2013

Curr Neurol Neurosci Rep

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Neoplastic leptomeningeal disease (NLD), which encompasses both primary and secondary leptomeningeal tumors, has a devastating impact on the life of cancer patients. The present diagnostic technical armamentarium is insufficient for early diagnosis of NLD. However, NLD may present with subtle neuro-ophthalmic features at a time of relatively small tumor burden, which gives the provider first encountering these patients the window of opportunity for early diagnosis and consequently improved life expectancy and quality of life of these patients. Therefore, familiarity with early, often subtle neuro-ophthalmic features is an essential tool for diagnosing these patients prior to the development of fixed deficits, which usually portend a dismal prognosis. Future evolving laboratory and neuroimaging technologies are expected to advance our understanding of underlying pathophysiology and early detection of NLD. This paper provides an up-to-date review and synthesis of the current literature with focus on neuro-ophthalmic features and their underlying pathophysiology.

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Reversible Distension of the Subarachnoid Space around the Optic Nerves in a Case of Idiopathic Hypertrophic Pachymeningitis

Cited by 6 publications

References 10 publications

Paquimeningitis relacionada con IgG4 y la visión. Reporte de caso

Paquimeningitis relacionada con IgG4 y la visión. Reporte de caso

An autopsy case of invasive sino‐orbital aspergillosis presenting the “tram‐track” sign and “donut configuration” in the orbital magnetic resonance imaging

Neuro-ophthalmologic Complications of Neoplastic Leptomeningeal Disease

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