Reversion towards benzimidazole susceptibility in Haemonchus contortus by resistance management strategies

Swarnkar, C.P.; Singh, D.; Khan, Farman Ali; Sharma, Savita

doi:10.56093/ijans.v91i3.114143

Cited by 2 publications

(1 citation statement)

References 17 publications

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“…The primary chemical constituent extracted from this plant is embelin, which carries excellent medicinal value and is used to cure various ailments and diseases 35 . Vaividang is used to treat obesity, mouth ulcers, fungus infections, mouth sores, pneumonia, mental disorders, constipation, and abdominal pain 36 . In addition, the plant has historically been used to treat skin conditions, toothaches, tonsillitis, arthritis, jaundice, bloating, and gastrointestinal nematodes 37 .…”

Section: Vaividang (Embelia Ribes)mentioning

confidence: 99%

Potential of Anthelmintic Herbal Drugs against Gastrointestinal Nematodes in Farm Animals: A Review

Sadr,

Ahmadi Simab,

Kasaei

et al. 2022

Farm Anim. Health Nutr.

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Gastrointestinal (GI) nematode infections are one of the most prevalent and significant problems in livestock worldwide. This study aimed to review the potential of anthelmintic herbal drugs against gastrointestinal nematodes in farm animals. Anthelmintic drugs are the most common method of controlling GI nematodes since they are simple, cheap, and provide therapeutic and prophylactic protection. However, the problem has become complicated due to the emergence of resistance to anthelmintic drugs because anthelmintic drugs are used indiscriminately to treat parasitic diseases. Anthelmintic resistance in GI nematodes of ruminants is a global problem. Many domestic animals possess multi-class resistance to all classes of anthelmintics. Synthetic anthelmintics could be unsafe as they can cause side effects and toxicity. Therefore, plants are used to develop and discover novel substances acting as anthelmintics. Herbal drugs have become increasingly popular because of their fewer side effects in recent years. Consequently, the demand for herbal formulations of anthelmintic drugs is increasing. The development of instrumental analysis accelerates the preparation of phytochemical constituents and their standardization, and this field is becoming critical for research.

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Section: Vaividang (Embelia Ribes)mentioning

confidence: 99%

Potential of Anthelmintic Herbal Drugs against Gastrointestinal Nematodes in Farm Animals: A Review

Sadr,

Ahmadi Simab,

Kasaei

et al. 2022

Farm Anim. Health Nutr.

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Effect of dietary tannin and protein concentration on resistance and resilience of chokla lambs against Haemonchus contortus

KHAN,

SAHOO

2023

Indian J of Anim Sci

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Feeding trial was conducted for 7 weeks using 5-6 months old chokla lambs reared in helminth free conditions. The source of condensed tannin was dried leaves of khejri (Prosopis cineraria). The animals were randomly allocated to six treatment groups: (1) Low protein (LP, 10.0% CP) throughout the trial, (2) high protein (HP, 18.4% CP) throughout the trial, (3) LP (for initial 3 weeks of the experiment) and then combination of LP and Khejri (K), (4) combination of LP and K throughout the trial, (5) HP (for initial 3 weeks of the experiment) and then combination of HP and K, and (6) combination of HP and K throughout the trial. At day 0, all groups were trickle infected with infective H. contortus larvae and subsequently with 400-500 larvae/animal three times per week for 6 weeks. Therewas no improvement in resilience as well as resistance of lambs fed with combination of LP concentrate and khejri leaves. Lambs (4-5) were given salvage treatment in each group. Bottle jaw condition was seen in two lambs in each group. There was similar reduction in both PCV and Hb parameters in all the three groups fed with LP concentrate without any influence of inclusion of khejri leaves in the diet. Similarly CT inclusion did not influence the faecal egg count (FEC). On the other hand, improvement in both resistance and resilience was observed in lambs fed with combination of HP concentrate and khejri leaves. Inclusion of khejri leaves in HP concentrate fed lambs significantly affected both PCV and Hb. Faecal egg count was also significantly affected. There was significant effect on average daily gains (ADG). Voluntary feed intake was obtained in collective pens. Although there was reduction in feed intake in all the groups during week 2 to 3, it was more evident in lambs kept on LP concentrate. Therefore, it was suggested that when tannin was included with HP concentrate, an additive effect was seen which resulted in increase in protein availability to the lambs.

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Reversion towards benzimidazole susceptibility in Haemonchus contortus by resistance management strategies

Cited by 2 publications

References 17 publications

Potential of Anthelmintic Herbal Drugs against Gastrointestinal Nematodes in Farm Animals: A Review

Potential of Anthelmintic Herbal Drugs against Gastrointestinal Nematodes in Farm Animals: A Review

Effect of dietary tannin and protein concentration on resistance and resilience of chokla lambs against Haemonchus contortus

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