Objective: To assess the influence of Quality improvement methods to improve the success rate of peripheral venous indwelling needle. Methods: 1613 patients were invested to join our study, they provided 2472 cases of peripheral venous indwelling needle. The time of they received services is from March 2019 to December 2019. They were divided into a control group (participant: n = 595, case: n = 1035) and an intervention group (participant: n =1018, case: n = 1437) according to this time, that patients were invested to join control group who receive services between March 2019 and June 2019, intervention group participants' service time is between June 2019 and December 2019. The control group participants receive routine care model in the PIVC process. About collection, the information includes the success rate of PIVC, complications situation and indwelling time of PIVC. Result: The success rate of PIVC assessment from researcher's report, they record the result of patient's PIVC. Intervention group has higher success rate than that of control group (71.95% vs 49.57%). Most complications were happened in PIVC process. it shows the research result of mainly 4 kinds of complication in the table, the result contains seepage, blocking pipe, take off the tube and phlebitis. In overall, intervention group patients have less complications cases and lower incidence of complications in each kind of complication, except as phlebitis result (p = 0.369). Conclusion: the quality improvement methods can improve the success rate of PIVC and reduce the complications cases of PIVC.