Review article: the current status of CT-guided needle biopsy of the spine

Saifuddin, Asif; Palloni, Valentina; Preez, Hannah du; Junaid, Syed

doi:10.1007/s00256-020-03584-9

Cited by 23 publications

(22 citation statements)

References 71 publications

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“…Our study finds that the accuracy of spinal biopsy is 83.3%, which is consistent with other studies with an accuracy of spinal biopsy ranging from 16.1% to 92.7% [3,[6][7][8][9][10][11][12][13][14][15][16][17][18][19]. Fluoroscopy-guided spinal biopsy has higher accuracy compared to CT-guided biopsy (86.6% vs. 80%), but it is not statistically significant (p = 0.731).…”

Section: Discussionsupporting

confidence: 89%

“…Thus far, the debate is still ongoing on which method of percutaneous biopsy is superior. Proponents of CT-guided biopsy argue that CT imaging provides excellent visualisation and demarcation of the spinal lesion, thus ensuring an optimal yield of biopsy [ 7 , 9 , 10 , 19 ]. Nonetheless, those who prefer fluoroscopy-guided spinal biopsy point out that CT exposes operators to excessive radiation with no significant yield difference between the two methods [ 3 ].…”

Section: Discussionmentioning

confidence: 99%

“…The difference in accuracy between the two methods might be influenced by other variables such as operator experience, level, size, and depth of the lesion, which are not captured in this study [ 3 ]. It is possible that those lesions requiring CT-guided biopsy are lesions that are difficult to be accessed via the posterolateral approach due to the proximity of the lesion to neural elements, hence lowering the accuracy of the biopsy [ 7 , 10 , 20 ].…”

Section: Discussionmentioning

confidence: 99%

“…Since the inception of percutaneous biopsy of the spinal lesion, it has become the procedure of choice owing to the less invasive nature of the procedure, thus allowing faster recovery of the patients [3][4][5]. A percutaneous spinal biopsy can be performed in two ways: either with computed tomography (CT)-guided or fluoroscopyguided [6][7][8][9][10]. Both methods have their advantages and disadvantages.…”

Section: Introductionmentioning

confidence: 99%

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Diagnostic Accuracy and Adequacy of Computed Tomography Versus Fluoroscopy-Guided Percutaneous Transpedicular Biopsy of Spinal Lesions

Zakaria@Mohamad¹,

Rahim²,

Kow³

et al. 2022

Cureus

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BackgroundTranspedicular biopsy of spinal lesions is imperative for the generation of a definite diagnosis. Thus far, literature comparing the accuracy and adequacy between fluoroscopy-guided and computed tomography (CT)-guided transpedicular biopsy of spinal lesions is scarce. We aim to compare the accuracy and adequacy of samples collected with the two techniques at the largest tertiary hospital in Malaysia. Materials and methodsA total of 60 patients (37 patients with spinal infection and 23 patients with spinal tumour) underwent percutaneous transpedicular biopsy of spinal lesions from January 2013 to December 2017 at a tertiary centre. Demographic data, biopsy method (fluoroscopy-guided and CT-guided), diagnosis, adequacy, and accuracy of samples obtained were assessed. ResultsAmong the 60 samples obtained, only two samples (3.3%) were deemed inadequate. There were 10 biopsy samples (16.7%) that were inaccurate. There was no statistical difference between fluoroscopy-guided and CT-guided transpedicular biopsy in terms of accuracy (p = 0.731) and adequacy (p = 0.492). ConclusionsFluoroscopy-guided and CT-guided transpedicular biopsy of spinal lesions offer similar accuracy and adequacy. Fluoroscopy-guided biopsy of the spinal lesion will be an option for spine surgeons when CTguided biopsy is not available.

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Section: Discussionsupporting

confidence: 89%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Diagnostic Accuracy and Adequacy of Computed Tomography Versus Fluoroscopy-Guided Percutaneous Transpedicular Biopsy of Spinal Lesions

Zakaria@Mohamad¹,

Rahim²,

Kow³

et al. 2022

Cureus

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“…Computed tomography (CT)-guided biopsy is proved to be an effective and safe tool for the diagnosis of spinal bone lesions [ 2 , 3 , 4 , 5 ]. Moreover, CT-guided biopsy showed a higher success rate than fluoroscopic-guided biopsy of the spine, and it is by far less invasive than open surgical biopsy.…”

Section: Introductionmentioning

confidence: 99%

Percutaneous CT-Guided Biopsy of the Craniovertebral Junction: Safety, Diagnostic Yield, and Technical Notes

2022

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The craniovertebral junction defined as the occiput, the atlas, and the axis is a complex bony region that contains vital neural and vascular structures. We report the experience of a single academic institution regarding CT-guided biopsy of this skeletal region. We reviewed all of the CT-guided biopsies performed in our department, completed in the craniovertebral junction. We collected data in regard to biopsy procedures, patients’ vital statistics, and histopathological diagnosis. In total, 16 patients (8M and 8F; mean age 52; range 16–86 years old) were included in this series. In eight patients, the lesions were located in the atlas vertebra (8/16—50%), in six patients in the axis (37.5%), and in two patients in the occiput (12.5%). No complications were observed during or after the procedures. All of the procedures were technically successful. The biopsy was diagnostic in 13/16 patients (81.3%): four metastatic lesions (25%—three breast and one prostate cancers), four multiple myeloma bone lesions (25%), three aneurismal bone cysts (18.8%), one aggressive hemangioma (6.3%), and one pseudogout (6.3%). Moreover, in two-thirds (66.6%) of non-diagnostic histological reports, malignancies were excluded. CT-guided percutaneous biopsy is a safe tool and allows obtaining a histological diagnosis, in most cases, even in the most delicate site of the human skeleton—the craniovertebral junction.

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