Review of cadmium transfers from soil to humans and its health effects in the Jamaican environment

Lalor, G. C.

doi:10.1016/j.scitotenv.2008.07.011

Cited by 89 publications

(43 citation statements)

References 96 publications

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“…A by-product from mining, smelting, and refining zinc, lead, and copper ores, cadmium use substantially increased during the last decades of the 20th century, particularly in nickel-cadmium batteries and in coating plastic stabilizers [59]. Soil contamination of cadmium is a main environmental problem because vegetables and grains bioconcentrate cadmium from soil, resulting in major cadmium exposure through diet and smoking [59,63]. Other dietary sources of cadmium include shellfish and organ meats.…”

Section: Epidemiologic Evidence Linking Toxic Metals and Cardiovasculmentioning

confidence: 99%

EDTA Chelation Therapy to Reduce Cardiovascular Events in Persons with Diabetes

et al. 2015

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The Trial to Assess Chelation Therapy (TACT) was a randomized double-blind placebo-controlled trial enrolling patients age ≥50 years with prior myocardial infarction. TACT used a 2 × 2 factorial design to study ethylene diamine tetraacetic acid (EDTA) chelation and high-dose vitamin supplementation. Chelation provided a modest but significant reduction in cardiovascular endpoints. The benefit was stronger and significant among participants with diabetes but absent in those without diabetes. Mechanisms by which chelation might reduce cardiovascular risk in persons with diabetes include the effects of EDTA chelation on transition and toxic metals. Transition metals, particularly copper and iron, play important roles in oxidative stress pathways. Toxic metals, in particular cadmium and lead, are toxic for the cardiovascular system. This review discusses the epidemiologic evidence and animal and human studies supporting the role of these metals in the development of diabetes and ischemic heart disease and potential ways by which EDTA chelation could confer cardiovascular benefit.

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Section: Epidemiologic Evidence Linking Toxic Metals and Cardiovasculmentioning

confidence: 99%

EDTA Chelation Therapy to Reduce Cardiovascular Events in Persons with Diabetes

et al. 2015

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“…This indicates that the risk for non carcinogenic health impact of Cd for these respondents is acceptable. According to (Lalor, 2008), there have been several cases of apparently high exposures to cadmium without accompanying health effects in France, Germany, United Kingdom (UK) and the United States (US). In addition, there may be numerous other confounding factors including cadmium bioavailability differences among vegetables, the percentage absorption of dietary cadmium in a population, genetics, lifestyle, diet and antagonistic or synergistic exposures to other elements, interpretations in "normal" ß-microglobulin and the effect of aging that may influence the occurrence of cadmium poisoning among the respondents.…”

Section: Health Risks Encountered By Respondents From Cadmium Exposurmentioning

confidence: 99%

Cadmium Exposure via Food Crops: A Case Study of Intensive Farming Area

Munisamy

Ismail

Praveena

2013

American Journal of Applied Sciences

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Cadmium (Cd) is ubiquitous in environment and may enter food chain through intense application of phosphate fertilizers to agricultural crops. A cross-sectional study was conducted at Kuala Terla and Blue Valley farming villages, Cameron Highlands to determine cadmium concentration in vegetables and soil and to determine the health risks among respondents. A total of 87 respondents were selected based on inclusive and exclusive criteria.A set of pre-tested questionnaires utilized to obtain socio-demographic information and to predict health risks faced by the respondents based on their vegetable ingestion rate. The Average Daily Dose (ADD) and Target Hazard Quotient (THQ) were determined in this study. Convenient sampling method was employed to obtain 15 paired soil and vegetable samples. Cadmium concentration in the samples was acid digested prior analysis using Flame Atomic Absorption Spectrophotometer (FAAS). The mean ± standard deviation concentrations of Cd in vegetable samples were 0.13±0.082 mg kg ). The findings on THQ demonstrated that all respondents are within the acceptable non-carcinogenic health risk (THQ<1). The results also exhibit that there is no correlation between cadmium in soils and vegetables. There are unlikely potential adverse health impacts arising from Cd through vegetables consumption in this study. Respondents are advised to have a medical check-up in order to determine Cd body burden thus eliminating the risks of acquiring cadmium related diseases.

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“…In some cases, however, few human health effects have been reported in countries with some of the highest naturally occurring soil Cd concentrations (Lalor et al, 2008). It is believed that a better understanding of the interaction of Cd with other elements may provide the key to understanding the effects of Cd on health.…”

Section: Studymentioning

confidence: 99%

Lead and Cadmium Levels in Liver, Kidney and Muscle of Harvested Wild Springbok (Antidorcus marsupialis) Under Extensive Management in Southern and Southeastern Namibia

Magwedere

Shimwino²,

Hemberger³

et al. 2013

South African Journal of Wildlife Research

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Of all animal tissues, livers and kidney constitute a special dilemma in that they have a tendency to bioaccumulate toxic metals such as arsenic (As), cadmium (Cd), lead (Pb) and mercury (Hg). Maximum concentrations (ML) for Hg, Pb, Cd and tin (Sn), but not As in foodstuffs are set by European Commission Regulations. The aims of this study were 1) to determine the concentrations of As, Cd, Pb and Hg in the livers and kidneys of nine cows from the index farm and 2) to combine the kidney Cd results from these 5 cows with those reported in an earlier Department of Agriculture Fisheries and Food (DAFF) report (n = 14 animals), and describe the trend in kidney Cd concentrations on the index farm over time.

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Review of cadmium transfers from soil to humans and its health effects in the Jamaican environment

Cited by 89 publications

References 96 publications

EDTA Chelation Therapy to Reduce Cardiovascular Events in Persons with Diabetes

EDTA Chelation Therapy to Reduce Cardiovascular Events in Persons with Diabetes

Cadmium Exposure via Food Crops: A Case Study of Intensive Farming Area

Lead and Cadmium Levels in Liver, Kidney and Muscle of Harvested Wild Springbok (Antidorcus marsupialis) Under Extensive Management in Southern and Southeastern Namibia

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