Review of Cherenkov imaging technology advances in radiotherapy: single-photon-level imaging in high ambient light and radiation backgrounds

Parks, Aubrey; Hallett, Jeremy; Niver, Alexander; Zhang, Rongxiao; Bruza, Petr; Pogue, Brian W.

doi:10.1117/1.bios.1.2.020901

Biophoton. Discovery

2024

DOI: 10.1117/1.bios.1.2.020901

|View full text |Cite

Review of Cherenkov imaging technology advances in radiotherapy: single-photon-level imaging in high ambient light and radiation backgrounds

Aubrey Parks,

Jeremy Hallett,

Alexander Niver

et al.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2024

Publication Types

Select...

Article1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

References 86 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Optimized scintillation imaging in low dose rate and bright room light conditions

Niver,

Bruza,

Pogue

2024

Biomed. Phys. Eng. Express

View full text Add to dashboard Cite

Objective. To develop a robust method for non-contact surface dosimetry during Total Body Irradiation (TBI) that uses an optimally paired choice of scintillator material with camera photocathode and can work insensitively to the normal ambient room lighting conditions (~500 Lux). Approach: This goal was approached by assessing the emission contrast of scintillator signal to background room ratio (SBR) detected by the camera, in the challening conditions of low dose rate TBI with high room lights. A total of 9 fast-response scintillators, 3 wavelength shifters, and 2 camera photocathodes were systematically tested to determine the optimal combination. The effects of room lights on the scintillator signal and the background signal were assessed to avoid signal saturation while retaining accurate dose measurement. A bandpass wavelength filter was then applied to reduce the effects on room lights and scintillator signal.Main Results: One scintillator (EJ262) combined with a blue-green sensitive photocathode camera and a 500nm band pass filter produced the greatest available scintillator SBR of 95 with maximal room lights on. The caveat is that this design rejects all patient Cherenkov light, which can be useful for visualizing the patient treatment. Another option which retained the Cherenkov signal but produced less available scintillator signal was found with another scintillator (EJ-260) and a red photocathode camera with SBR of 35, but a narrow bandpass filter is required to make it work in ambient room lights, which addition will also remove most of the Cherenkov signal. Significance: Non-contact scintillator imaging can be used for surface dosimetry in TBI with appropriate pairing of scintillator emission spectrum and camera photocathode sensitivity or optical filtering range.

show abstract

Optimized scintillation imaging in low dose rate and bright room light conditions

Niver,

Bruza,

Pogue

2024

Biomed. Phys. Eng. Express

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Review of Cherenkov imaging technology advances in radiotherapy: single-photon-level imaging in high ambient light and radiation backgrounds

Cited by 1 publication

References 86 publications

Optimized scintillation imaging in low dose rate and bright room light conditions

Optimized scintillation imaging in low dose rate and bright room light conditions

Contact Info

Product

Resources

About