Review of fat grafting and the fate of the subperiostal fat graft

Önel, Defne; Emekli, Ufuk; Çizmeci, M. Orhan; Aköz, Funda; Bılgıç, Bilge

doi:10.1007/s00238-003-0507-8

Cited by 3 publications

(1 citation statement)

References 17 publications

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“…Therefore, in many studies, the inguinal fat pad was harvested surgically in en bloc fashion and trimmed into small pieces before the reimplantation process. 17,18 Although this method does not properly reflect the liposuction procedure as harvesting method, it is one of the most commonly performed methods providing the researcher significant amount of autologous graft in rat model. In our study, we harvested the fat grafts in en bloc fashion and diced them into small pieces with scalpel.…”

Section: Discussionmentioning

confidence: 99%

Effects of Tumescent Solution on Fat Survival

et al. 2017

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Autologous fat transfer is a commonly used procedure in plastic surgery practice. The long-term survival rate of fat grafts is the most important issue for satisfactory results. The presented study includes the effects of different tumescent solutions on long-term fat graft survival. A total of 24 rats were divided into four groups: sham, lidocaine, adrenaline, and lidocaine + adrenaline groups. In all groups except the sham group, right inguinal fat pad was harvested 10 minutes after injecting 5 cc of the appropriate tumescent solution. The fat pad was trimmed and reimplanted to the interscapular area. After 3 months, fat pad was reharvested and sent for histopathologic evaluation. The harvested fat grafts were weighted in both surgical sessions. A significant difference was observed in comparison of fat grafts weights between the initial operation and the postoperative third month (p = 0.002). By intergroup comparisons, a significant difference was observed between sham and adrenaline groups (p = 0.002) and between sham and lidocaine + adrenaline groups (p = 0.007). No statistical difference was observed by the comparison of TUNNEL results (p = 0.663). The histopathologic evaluation of the specimens revealed similar results between groups. The injection of tumescent solutions containing only lidocaine before fat harvesting yields similar long-term fat graft survival rates in comparison to the conduction of surgical procedure without injecting any tumescent fluid. However, the injection of solutions containing adrenaline with or without lidocaine may decrease the long-term survival rates of fat autografts.

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Section: Discussionmentioning

confidence: 99%