Review of functional materials for potential use as wearable infection sensors in limb prostheses

Devaraj, Harish; Aw, Kean C.; McDaid, Andrew

doi:10.1007/s13534-019-00132-w

Cited by 7 publications

(6 citation statements)

References 150 publications

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“…Their unique properties and broad-spectrum antimicrobial activity make them valuable in healthcare applications, including the self-hygiene of sports prostheses for children. By incorporating AgNPs into prosthetic materials, a hygienic environment can be promoted, reducing the risk of infections and enhancing the overall well-being (Akhavan et al, 2018;Sarraf et al, 2018;Vale et al, 2019;Xie et al, 2019;Devaraj et al, 2020;Sohi et al, 2021;Bee et al, 2022;Nathanael et al, 2022;Padmanabhan et al, 2022;Rodriguez Barroso et al, 2023).…”

Section: Journal Of Disability Research 2023mentioning

confidence: 99%

A Review of Children’s Prosthetic Self-hygiene Using Antibacterial Silver Nanoparticles (AgNPs)

Alnaser,

Siddiqui,

Aijaz

et al. 2023

Journal of Disability Research

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Sports prostheses represent a critical facet in enhancing the mobility and quality of life for children with limb loss. However, prolonged usage of these prosthetic devices introduces substantial challenges related to hygiene and the heightened risk of infection. This comprehensive review endeavors to delve into the untapped potential of utilizing antibacterial silver nanoparticles (AgNPs) to foster self-hygiene practices in pediatric sports prostheses. AgNPs have emerged as a compelling area of research, largely attributable to their formidable antibacterial properties, offering revolutionary prospects in the realm of antibacterial therapy. Central to this exploration is an in-depth analysis of their antibacterial activity, elucidating their intricate mechanisms of action against bacterial agents. The unique physicochemical attributes, characterized by their diminutive size and expansive surface area, synergize to elevate their antibacterial efficacy significantly. The antibacterial mechanisms involve the controlled release of silver ions, which disrupt bacterial cell membranes, impede vital cellular processes, and provoke oxidative stress within the pathogens. Moreover, they exhibit the propensity for synergistic interactions when employed in tandem with conventional antibiotics, thereby positioning themselves as promising candidates for combination therapy. This review further encompasses a comprehensive survey of diverse methodologies employed for the synthesis of AgNPs and their multifarious application in various domains, including the realm of prosthetics and medicine. Nevertheless, as with any emerging technology, the implementation of AgNPs does not come without its challenges. Issues pertinent to the stability of AgNPs, potential toxicity concerns, and the development of bacterial resistance necessitate critical consideration for their successful integration into pediatric sports prostheses. In summation, AgNPs epitomize a compelling arsenal of antibacterial agents, propelling the possibilities of innovative therapeutic strategies in the battle against bacterial infections. This review underscores their remarkable potential while underscoring the imperative need for further research and development to unlock their full efficacy in the context of pediatric sports prostheses and beyond.

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Section: Journal Of Disability Research 2023mentioning

confidence: 99%

A Review of Children’s Prosthetic Self-hygiene Using Antibacterial Silver Nanoparticles (AgNPs)

Alnaser,

Siddiqui,

Aijaz

et al. 2023

Journal of Disability Research

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“…"Advancements in Functional Materials for Potential as Wearable Infection Sensors in Limb Prostheses" introduces the integration of infection sensors to prostheses for detecting and preventing infections for both traditional socket and OI prostheses. Since pathogenic volatiles have been identified as potent stimuli, this paper reviews the current techniques in the field of infection sensing, specifically focusing on identifying portable and flexible sensors with the potential to be integrated into prosthesis designs [4]. V. The paper on "Non-Radiative Healing Assessment Techniques for Fractured Long Bones and Osseointegrated Implant" provides an overview of the fracture healing process of long bones, a review of work that proposed appropriate physical parameters for the assessment of healing and highlights some recent work that reported on the development of nonradiative techniques for healing assessment.…”

Section: Prefacementioning

confidence: 99%

Special issue of biomedical engineering letters on advances in intelligent prostheses

et al. 2020

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“…Metals and other alloys are currently being used to make prostheses for modern sports that imitate the functions of a real human limb (Hagberg et al, 2005;Jayaraman et al, 2019;Krausz and Hargrove, 2019;Parga and Yu, 2019;Villarreal and Gregg, 2019;Damerla et al, 2022;Gomez-Correa and Cruz-Ortiz, 2022). Artificial limbs are more expensive than mechanical prostheses, which is a disadvantage for lower-middle-class economies because they will not be able to afford such high prices (Mauroy et al, 2012;Devaraj et al, 2020;Migliore et al, 2020;Powell et al, 2020). Nevertheless, they provide necessary features and help close the gap between mechanical and automated prostheses.…”

Section: Introductionmentioning

confidence: 99%

Static Behavior of a Prosthetic Running Blade Made from Alloys and Carbon Fiber

Siddiqui¹,

Arifudin²,

Alnaser³

et al. 2023

Journal of Disability Research

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Prosthetic running blades offer a solution for individuals with disabilities to engage in sports, benefiting them both psychologically and physiologically. Furthermore, a good prosthetic running blade in terms of performance and cost is rarely available to all disabled persons. In this study, we have examined how various materials impact the static behavior of the prosthetic running blade. A finite element numerical analysis was conducted on a prosthetic design to investigate this effect. We have used different materials for investigation such as aluminum alloy (2024 T4), stainless steel (AISI 316), carbon fiber, and titanium alloy (grade 5), under different load conditions. The load conditions have been varied mainly to three conditions, namely, rest (700 N), walking (1400 N), and running (2100 N). In our experimental design, we studied total deformation, equivalent stress, and strain energy to understand the performance based on material choice. It was noticed that the aluminum alloy (2024 T4) blade goes under much deformation when compared to titanium- and carbon fiber-made running blades. The least amount of overall deformation occurs in carbon fiber under varying load conditions. Carbon fiber appears to be the most profitable option due to its lowest cost per running blade. Titanium alloy grade 5, carbon fiber, AISI 316 stainless steel, and aluminum 2024 T4 alloy cost a total of 78.1, 48.5, 67.6, and 20.9 USD, respectively. It is evident that titanium alloy materials carry a higher price compared to alternative materials.

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Review of functional materials for potential use as wearable infection sensors in limb prostheses

Cited by 7 publications

References 150 publications

A Review of Children’s Prosthetic Self-hygiene Using Antibacterial Silver Nanoparticles (AgNPs)

A Review of Children’s Prosthetic Self-hygiene Using Antibacterial Silver Nanoparticles (AgNPs)

Special issue of biomedical engineering letters on advances in intelligent prostheses

Static Behavior of a Prosthetic Running Blade Made from Alloys and Carbon Fiber

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