Over the last decades, the use of the alternative fuels was one of the main research activities for specialists in the field of internal combustion engines. The development of the modern automotive engines is constantly challenged by the more severe emission legislation. The engine emissions levels and the fuel efficiency are directly influenced by the engine operation, reproduction of the combustion phases from one cycle to other, cyclic dispersion during combustion process being important. In general, the use of alternative fuels in internal combustion engines provides an improvement of the energetic and pollution performance, or just a slight improvement of them, but the study of the combustion process must be completed with aspects regarding the cyclic variability. In particular, using this alternative fuel, a study of cyclic variation of the combustion process would be necessary in order to establish if the normal operation of the engine can be ensured. The paper presents some aspects of the analysis of the cyclic variability at a spark ignition engine fuelled with gasoline and hydrogen. During the engine operation at the regime of 2500 rev/min speed and 55% engine load, a number of 250 consecutive combustion cycles was recorded for classic fuel use and for hydrogen use. The coefficient of cyclic variation (CCV) or the coefficient of variation (COV) is determined for different combustion parameters such as maximum pressure, maximum pressure rise rate and mass fraction burned, defined by angles at which the conventional fractions of 10%, 50% and 90% of the heat of reaction is released. Thus, the values of the COV for maximum pressure (COV)pmax, maximum pressure rise rate (COV)dp/dα, angles of 10, 50 and 90% heat release as (COV)10%, (COV)50% and (COV)90% were calculated and compared with the admissible limit of 10%. The combustion variability analysis establishes the limits of the normal operation of the spark ignition engine fuelled with gasoline and hydrogen compared with the classic fuelling method.