Review of idiopathic pancreatitis

Lee, Jason Kihyuk; Enns, Robert

doi:10.3748/wjg.v13.i47.6296

Cited by 61 publications

(45 citation statements)

References 279 publications

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“…Other causes are considerably more rare [19][20][21]. The highest rates of gallstone-related AP are reported in Mediterranean countries: Greece, Italy, Croatia and Spain [1].…”

Section: Causes Of Morbiditymentioning

confidence: 99%

Epidemiology of acute pancreatitis in Poland – selected problems

Kozieł¹,

Głuszek²

2016

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In recent years in many European countries, an increase has been observed in the incidence of acute pancreatitis (AP). Analysis of the results of scarce Polish epidemiological studies suggests that Poland belongs to the countries with the highest incidence rate -72.1/100 000. The incidence rate in the Kielce region is 99.9/100 000 and 79.7/100 000 patients who experienced the first episode of pancreatitis. The main cause of contracting the disease is gallstones, responsible for 34% of cases, while alcohol is the cause of AP in 24.1% of patients. In recent years, an increase has been noted in the incidence of AP with a severe course. Although in the majority of patients the course of the disease is mild, in the severe form mortality remains within the range 30-60%. StreszczenieW ostatnich latach obserwuje się wzrost zachorowań na ostre zapalenie trzustki (OZT) w wielu krajach. Analiza wyników nielicznych polskich badań epidemiologicznych pozwala przypuszczać, że Polska należy do krajów o jednym z najwyższych współczynników zachorowalności -72,1/100 000. Współczynnik zachorowalności w województwie świętokrzyskim wynosi 99,9/100 000. Po raz pierwszy na OZT chorowało 79,7/100 000 osób. Główną przyczyną zachorowania polskich pacjentów jest kamica żółciowa, która odpowiada za 34% przypadków. Alkohol jest przyczyną OZT u 24,1% chorych. Stwierdza się ponadto wzrost częstości występowania OZT o ciężkim przebiegu. Chociaż u większości pacjentów choroba ma przebieg łagodny, to w przypadku ciężkiej postaci śmiertelność kształtuje się na poziomie 30-60%.

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“…Other causes are considerably more rare [19][20][21]. The highest rates of gallstone-related AP are reported in Mediterranean countries: Greece, Italy, Croatia and Spain [1].…”

Section: Causes Of Morbiditymentioning

confidence: 99%

Epidemiology of acute pancreatitis in Poland – selected problems

Kozieł¹,

Głuszek²

2016

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“…Pancreatic adenocarcinoma can also present as pancreatitis, and the acute attacks may precede the diagnosis of overt malignancy in the gland by several months [15]. It has been estimated that approximately 5-14% of patients with benign or malignant pancreatobiliary tumors are initially diagnosed as idiopathic AP [16]. Unexplained recurrent pancreatitis from the middle age should raise the suspicion of underlying tumor, especially in patients with worrisome associated symptoms (weight loss, new-onset diabetes).…”

Section: Pancreatic/ampullary Obstructionmentioning

confidence: 99%

“…Pancreatic-type SOD ranges from patients with pancreatic-type pain, raised serum amylase or lipase and pancreatic duct dilatation (Type I), to those with pancreatic-type pain and no other abnormalities (Type III). The importance of this condition as cause of recurrent AP is not clearly established, although it has been considered to cause up to one third of all cases of idiopathic pancreatitis [16]. …”

Section: Sphinter Of Oddi Dysfunctionmentioning

confidence: 99%

Etiology of Pancreatitis and Risk Factors

Lauret¹,

Rodríguez-Peláez²,

Sáez³

2015

Acute and Chronic Pancreatitis

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“…Sphincter of Oddi manometry may be performed, and if a diagnosis is confirmed, endoscopic sphincterotomy should be performed. 94 For pancreas divisum, minor sphincterotomy and/or pancreatic duct stent may be performed. 95 ERCP typically does not have a role in those patients with a single attack of acute pancreatitis, as significant complications may occur due to the ERCP itself.…”

Section: Endoscopymentioning

confidence: 99%

Acute pancreatitis

Munsell

Buscaglia

2010

Journal of Hospital Medicine

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Acute pancreatitis is a common disease most frequently caused by gallstone disease or excess alcohol ingestion. Diagnosis is usually based on characteristic symptoms, often in conjunction with elevated serum pancreatic enzymes. Imaging is not always necessary, but may be performed for many reasons, such as to confirm a diagnosis of pancreatitis, rule out other causes of abdominal pain, elucidate the cause of pancreatitis, or to evaluate for complications such as necrosis or pseudocysts. Though the majority of patients will have mild, self‐limiting disease, some will develop severe disease associated with organ failure. These patients are at risk to develop complications from ongoing pancreatic inflammation such as pancreatic necrosis, fluid collections, pseudocysts, and pancreatic duct disruption. Validated scoring systems can help predict the severity of pancreatitis, and thus, guide monitoring and intervention.Treatment of acute pancreatitis involves supportive care with fluid replacement, pain control, and controlled initiation of regular food intake. Prophylactic antibiotics are not recommended in acute pancreatitis if there is no evidence of pancreatic infection. In patients who fail to improve, further evaluation is necessary to assess for complications that require intervention such as pseudocysts or pancreatic necrosis. Endoscopy, including ERCP and EUS, and/or cholecystectomy may be indicated in the appropriate clinical setting. Ultimately, the management of the patient with severe acute pancreatitis will require a multidisciplinary approach. Journal of Hospital Medicine 2010;5:241–250. © 2010 Society of Hospital Medicine.

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Review of idiopathic pancreatitis

Cited by 61 publications

References 279 publications

Epidemiology of acute pancreatitis in Poland – selected problems

Epidemiology of acute pancreatitis in Poland – selected problems

Etiology of Pancreatitis and Risk Factors

Acute pancreatitis

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