Review of Injectable Materials for Soft Tissue Augmentation

Homicz, Mark R.; Watson, Deborah

doi:10.1055/s-2004-822955

Cited by 88 publications

(96 citation statements)

References 35 publications

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“…In addition, because of high resorption, 23 fat is usually injected in a substantial amount using a large-bore needle (14-gauge to 18-gauge), aiming to overcorrect the cosmetic defect. 24 The high volume and high pressure of this injection seem responsible for multifocal and complete obstruction of the ophthalmic artery and its branches after autologous fat injections.…”

Section: Discussionmentioning

confidence: 99%

Iatrogenic Occlusion of the Ophthalmic Artery After Cosmetic Facial Filler Injections

et al. 2014

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for the Korean Retina Society IMPORTANCE Iatrogenic occlusion of the ophthalmic artery and its branches is a rare but devastating complication of cosmetic facial filler injections.OBJECTIVE To investigate clinical and angiographic features of iatrogenic occlusion of the ophthalmic artery and its branches caused by cosmetic facial filler injections. DESIGN, SETTING, AND PARTICIPANTS Data from 44 patients with occlusion of the ophthalmic artery and its branches after cosmetic facial filler injections were obtained retrospectively from a national survey completed by members of the Korean Retina Society from 27 retinal centers. Clinical features were compared between patients grouped by angiographic findings and injected filler material. MAIN OUTCOMES AND MEASURESVisual prognosis and its relationship to angiographic findings and injected filler material.RESULTS Ophthalmic artery occlusion was classified into 6 types according to angiographic findings. Twenty-eight patients had diffuse retinal and choroidal artery occlusions (ophthalmic artery occlusion, generalized posterior ciliary artery occlusion, and central retinal artery occlusion). Sixteen patients had localized occlusions (localized posterior ciliary artery occlusion, branch retinal artery occlusion, and posterior ischemic optic neuropathy). Patients with diffuse occlusions showed worse initial and final visual acuity and less visual gain compared with those having localized occlusions. Patients receiving autologous fat injections (n = 22) had diffuse ophthalmic artery occlusions, worse visual prognosis, and a higher incidence of combined brain infarction compared with patients having hyaluronic acid injections (n = 13).CONCLUSIONS AND RELEVANCE Clinical features of iatrogenic occlusion of the ophthalmic artery and its branches following cosmetic facial filler injections were diverse according to the location and extent of obstruction and the injected filler material. Autologous fat injections were associated with a worse visual prognosis and a higher incidence of combined cerebral infarction. Extreme caution and care should be taken during these injections, and physicians should be aware of a diverse spectrum of complications following cosmetic facial filler injections.

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Section: Discussionmentioning

confidence: 99%

Iatrogenic Occlusion of the Ophthalmic Artery After Cosmetic Facial Filler Injections

et al. 2014

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“…[7][8][9][10] Bovine collagen has been FDA-approved since 1981 for treating scars, lines, and wrinkles, while porcine collagen has been FDA-approved since June 2008. Collagen can be mixed with polymethylmethacrylate microspheres (Artefill).…”

Section: Collagen and Collagen Mixed With Polymethylmethacrylatementioning

confidence: 99%

Imaging Features of Midface Injectable Fillers and Associated Complications

Ginat

Schatz

2012

AJNR Am J Neuroradiol

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“…The ultrasound showed to be an appropriate tool to assess the product behavior in vivo, since it allows its localization and measurement, in addition to being a painless and non-invasive method [16][17][18][19][20][21][22][23][24][25][26][27]. Its durability in up to 01 year after application is demonstrated because no significant reduction in the volume deposited in the procedure location was observed.…”

Section: Ultrasoundmentioning

confidence: 99%

Injectable Polyethylene Glycol Gel as Dermal Filler: 01 Year Clinical and Ultrasound Follow-Up

Addor¹,

Neri²

2016

J Clin Exp Dermatol Res

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Facial alterations that occur with aging are result of combined effects of soft tissue atrophy with loss of facial volume, gravitational factor and decrease of elastic tissue. In order to minimize these alterations, minimally invasive procedures such as cutaneous filling have been gaining space in clinical practice. In 2008, Scientech CorporationItalia introduced hydrogel of polyethylene glycol (PEG) REMAKE ® as cutaneous filler. This prospective study was developed to prove the effectiveness, safety and durability over the 12 months after the application of PEG hydrogel, commercialized under the name of REMAKE ® . 40 female volunteers were included, between 30 and 60 years, with signs of malar region volume loss between 2 and 3 (Raspaldo's classification) and Nasogenian furrow accentuation, with score between 2 and 3 (Day and collaborators' classification). No patient had carried out procedures of temporary filling for 1 year or permanent filling at any time. Objective parameters always show the scale of the improvement and an evaluation was selected through ultrasound exams and surface scan for evaluation of size and depth of wrinkles improvement. Evaluations by the US were carried out for 30, 120 and 360 days of product use, in a pilot group of 18 patients randomly selected to measure the product in the application plan and numerically assess alterations of volume (absorption/migration). Its durability of up to 01 year after application is proved when no significant reduction.

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Review of Injectable Materials for Soft Tissue Augmentation

Cited by 88 publications

References 35 publications

Iatrogenic Occlusion of the Ophthalmic Artery After Cosmetic Facial Filler Injections

Iatrogenic Occlusion of the Ophthalmic Artery After Cosmetic Facial Filler Injections

Imaging Features of Midface Injectable Fillers and Associated Complications

Injectable Polyethylene Glycol Gel as Dermal Filler: 01 Year Clinical and Ultrasound Follow-Up

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