Review of metastasis to meningiomas with case examples

Sættem, Magnus; Sundstrøm, Terje; Sæle, Anna.K.Myrmel; Mahesparan, Rupavathana

doi:10.1016/j.bas.2024.102862

Brain and Spine

2024

DOI: 10.1016/j.bas.2024.102862

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Review of metastasis to meningiomas with case examples

Magnus Sættem,

Terje Sundstrøm,

Anna.K.Myrmel Sæle

et al.

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2024

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Cited by 1 publication

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A challenging discrimination of an intensely [18F]PSMA-1007-avid solitary lesion at the skull base in a patient with biochemical recurrence of prostate cancer

Novruzov,

Niegisch,

Pauck

et al. 2024

BJR|Case Reports

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Prostate adenocarcinoma metastasis to brain has been reported to occur only up to 0.6% of patients and these are mostly diagnosed in autopsy series. In the setting of biochemical recurrence of prostate cancer, a suspected PSMA-avid lesion in the brain is still strongly suggestive of an intracranial metastasis of prostate cancer. This needs, however, a thoroughly recurrency work-up due to other potentially PSMA-avid cranial lesions, as PSMA initially was developed for the imaging of primary CNS tumors. We report of a challenging clinical case of a 71-year-old-patient with a strongly PSMA-avid lesion at the skull base. Given the medical history of a meningioma at the skull base, the further diagnostic work-up with MRI could still not rule out a malignancy, so that the patient needed to undergo a surgical excision of the tumor mass. The histological and immunohistochemical examinations revealed a relapsed CNS WHO grade 1 meningioma. From the aspect of molecular imaging and critical analysis of regular clinical care in a third-level university hospital, we consider this result very intriguing. Hence, we analyze the decision-making process and clinical course of this case in the light of molecular imaging findings.

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A challenging discrimination of an intensely [18F]PSMA-1007-avid solitary lesion at the skull base in a patient with biochemical recurrence of prostate cancer

Novruzov,

Niegisch,

Pauck

et al. 2024

BJR|Case Reports

View full text Add to dashboard Cite

show abstract

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Review of metastasis to meningiomas with case examples

Cited by 1 publication

References 40 publications

A challenging discrimination of an intensely [18F]PSMA-1007-avid solitary lesion at the skull base in a patient with biochemical recurrence of prostate cancer

A challenging discrimination of an intensely [18F]PSMA-1007-avid solitary lesion at the skull base in a patient with biochemical recurrence of prostate cancer

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