Review of Natural and synthetic tyrosinase inhibitors

Namjooyan, Foroogh; Moosavi, H; Taherian, Azadeh

doi:10.1055/s-0031-1282716

Cited by 1 publication

(1 citation statement)

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“…Previous studies on A. rosea plant were focused on its biological activities such as hepatotoxicity (Hussain et al 2014), tyrosinase inhibitory activity (Namjooyan et al 2011), antibacterial activity (Seyyednejad et al 2010). Studies on antiproliferative activity of A. rosea plant are not sufficient.…”

Section: Resultsmentioning

confidence: 99%

Antiproliferative activities of several plant extracts from Turkey on rat brain tumor and human cervix carcinoma cell lines

Yağlıoğlu

Eser

Teki̇n

et al. 2015

Frontiers in Life Science

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Turkey has a wide range of flora and fauna due to its climatic diversity. Medicinal plants from Turkey have been used since ancient times for their primary health care. In this study, we examined antiproliferative activities of the extracts from Crataegus monogyna, Vitis vinifera, Glycrrhiza glabra, Alnus glutinosa L. gaertn, and Alcea rosea against rat brain tumor (C6) and human cervical cancer (HeLa) cell lines. The results were compared with the standard anticancer drugs 5-Flurouracil (5-FU) and Cisplatin. C. monogyna, V. vinifera and A. rosea exhibited better antiproliferative activity than 5-FU and cisplatin at 100-75 μg/mL concentrations, against C6 cell lines. On the other hand, C. monogyna and V. vinifera extracts showed considerable antiproliferative activity against HeLa cells compared with 5-FU and cisplatin at 100-75 μg/mL. It can be suggested that, C. monogyna, A. glutinosa L. gaertn, V. vinifera and A. rosea extracts could be developed as an anticancer drug.

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Section: Resultsmentioning

confidence: 99%