Review of non-invasive continuous glucose monitoring based on impedance spectroscopy

Huang, Jiamei; Ying, Zhang; Wu, Jayne

doi:10.1016/j.sna.2020.112103

Cited by 73 publications

(53 citation statements)

References 27 publications

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“…There are other approaches such as bio-impedance spectroscopy [142], microwave spectroscopy [143], ultrasound [144], and heat propagation [145] which shows strong potentials to be commercialized, probably in coming years. In order to demonstrate the usefulness of any of these techniques, the demonstrators still have to become technologically more complete, they must be tested with a large number of individuals in real-world scenarios, and the measurement instability resulting from human physiological variability must be investigated.…”

Section: Miscellaneous Techniquesmentioning

confidence: 99%

Comprehensive Review on Wearable Sweat-Glucose Sensors for Continuous Glucose Monitoring

Zafar

Channa

Jeoti

et al. 2022

Sensors

163

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The incidence of diabetes is increasing at an alarming rate, and regular glucose monitoring is critical in order to manage diabetes. Currently, glucose in the body is measured by an invasive method of blood sugar testing. Blood glucose (BG) monitoring devices measure the amount of sugar in a small sample of blood, usually drawn from pricking the fingertip, and placed on a disposable test strip. Therefore, there is a need for non-invasive continuous glucose monitoring, which is possible using a sweat sensor-based approach. As sweat sensors have garnered much interest in recent years, this study attempts to summarize recent developments in non-invasive continuous glucose monitoring using sweat sensors based on different approaches with an emphasis on the devices that can potentially be integrated into a wearable platform. Numerous research entities have been developing wearable sensors for continuous blood glucose monitoring, however, there are no commercially viable, non-invasive glucose monitors on the market at the moment. This review article provides the state-of-the-art in sweat glucose monitoring, particularly keeping in sight the prospect of its commercialization. The challenges relating to sweat collection, sweat sample degradation, person to person sweat amount variation, various detection methods, and their glucose detection sensitivity, and also the commercial viability are thoroughly covered.

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Section: Miscellaneous Techniquesmentioning

confidence: 99%

Comprehensive Review on Wearable Sweat-Glucose Sensors for Continuous Glucose Monitoring

Zafar

Channa

Jeoti

et al. 2022

Sensors

163

View full text Add to dashboard Cite

show abstract

“…The ability to quickly and accurately monitor glucose levels in the blood is critical for diagnosing, managing, and treating diabetes [113]. If left unchecked, people with diabetes may experience fatal kidney failures, blindness, heart attacks, and strokes [114].…”

Section: Glucosementioning

confidence: 99%

Recent Advances in Layered Double Hydroxide-Based Electrochemical and Optical Sensors

Kim

Varga

Adhikari³

et al. 2021

Nanomaterials

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Layered double hydroxides (LDHs) have attracted considerable attention as promising materials for electrochemical and optical sensors owing to their excellent catalytic properties, facile synthesis strategies, highly tunable morphology, and versatile hosting ability. LDH-based electrochemical sensors are affordable alternatives to traditional precious-metal-based sensors, as LDHs can be synthesized from abundant inorganic precursors. LDH-modified probes can directly catalyze or host catalytic compounds that facilitate analyte redox reactions, detected as changes in the probe’s current, voltage, or resistance. The porous and lamellar structure of LDHs allows rapid analyte diffusion and abundant active sites for enhanced sensor sensitivity. LDHs can be composed of conductive materials such as reduced graphene oxide (rGO) or metal nanoparticles for improved catalytic activity and analyte selectivity. As optical sensors, LDHs provide a spacious, stable structure for synergistic guest–host interactions. LDHs can immobilize fluorophores, chemiluminescence reactants, and other spectroscopically active materials to reduce the aggregation and dissolution of the embedded sensor molecules, yielding enhanced optical responses and increased probe reusability. This review discusses standard LDH synthesis methods and overviews the different electrochemical and optical analysis techniques. Furthermore, the designs and modifications of exemplary LDHs and LDH composite materials are analyzed, focusing on the analytical performance of LDH-based sensors for key biomarkers and pollutants, including glucose, dopamine (DA), H2O2, metal ions, nitrogen-based toxins, and other organic compounds.

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“…It is expected that biosensors and hand-held bioassays will be cheaper that the standard instrumental methods, will be applicable without expensive measuring or sample-processing devices and will require neither elaborative sample or reagents processing nor demands on staff training or education. Currently, there are methods and biosensors available for the rapid detection of glucose and glycemia level determination, and these devices exert good analytical parameters, simplicity and low costs, and noninvasive methods for measuring glucose have even been developed [ 58 , 59 , 60 , 61 , 62 , 63 , 64 , 65 , 66 ]. Though the methods for measuring glucose are promising and many of them are currently available in the market, they have limitations in the interpretation of glucose level, as discussed in the previous chapter.…”

Section: Biosensors and Bioassays Measuring Hba 1cmentioning

confidence: 99%

Glycated Hemoglobin and Methods for Its Point of Care Testing

Pohanka

2021

Biosensors

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Glycated hemoglobin (HbA1c) is a product of the spontaneous reaction between hemoglobin and elevated glucose levels in the blood. It is included among the so-called advanced glycation end products, of which is the most important for the clinical diagnosis of diabetes mellitus, and it can serve as an alternative to glycemia measurement. Compared to the diagnosis of diabetes mellitus by glycemia, the HbA1c level is less influenced by a short-term problem with diabetes compensation. Mass spectroscopy and chromatographic techniques are among the standard methods of HbA1c level measurement. Compared to glycemia measurement, there is lack of simple methods for diabetes mellitus diagnosis by means of the HbA1c assay using a point-of-care test. This review article is focused on the surveying of facts about HbA1c and its importance in diabetes mellitus diagnosis, and surveying standard methods and new methods suitable for the HbA1c assay under point-of-care conditions. Various bioassays and biosensors are mentioned and their specifications are discussed.

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Review of non-invasive continuous glucose monitoring based on impedance spectroscopy

Cited by 73 publications

References 27 publications

Comprehensive Review on Wearable Sweat-Glucose Sensors for Continuous Glucose Monitoring

Comprehensive Review on Wearable Sweat-Glucose Sensors for Continuous Glucose Monitoring

Recent Advances in Layered Double Hydroxide-Based Electrochemical and Optical Sensors

Glycated Hemoglobin and Methods for Its Point of Care Testing

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