2023
DOI: 10.1117/1.jbo.28.8.080901
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Review of optical reporters of radiation effects in vivo: tools to quantify improvements in radiation delivery technique

Abstract: Radiation damage studies are used to optimize radiotherapy treatment techniques. Although biological indicators of damage are the best assays of effect, they are highly variable due to biological heterogeneity. The free radical radiochemistry can be assayed with optical reporters, allowing for high precision titration of techniques.Aim: We examine the optical reporters of radiochemistry to highlight those with the best potential for translational use in vivo, as surrogates for biological damage assays, to info… Show more

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References 118 publications
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