Review of Pharmacological Properties and Chemical Constituents of <i>Pastinaca sativa</i>

Kenari, Hoorieh Mohammadi; Kordafshari, Gholamreza; Moghimi, Maryam; Eghbalian, Fatemeh; TaherKhani, Dariush

doi:10.3831/kpi.2021.24.1.14

Cited by 28 publications

(17 citation statements)

References 34 publications

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“…Esculetin is also a potent agent in protecting cells from ROS-mediated Abeta-damage [13]. In another study, esculetin is effective in protecting cells against DNA damage induced by oxidative stress [14]. Esculetin has the effect of promoting glucose metabolism and mediates adipocyte apoptosis by the mitochondrial pathway initiating the apoptotic process of 3T3-L1 adipocytes [15].…”

Section: Resultsmentioning

confidence: 99%

Isolation and Characterization of Phytochemicals of Pastinaca Umbrosa

Mammadova

Serkerov

2022

JCPRM

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The Pastinaca genus belongs to Umbelliferae family. Pastinaca umbrosa grows widely in the north-west, west and center of Azerbaijan. In the present study, phytochemicals of the plants have been isolated and their structures have been elucidated. The mix of extractive substances was obtained by finely cutting the body of Pastinaca umbrosa, then drying in the room conditions (200 g) and extracting by acetone 3 times (3 days for each time). The acetone was filtered and evaporated on a water bath. The residue was a dark-brown resin (12 g, 6% yield). The resin (12 g) was dissolved in CHCl3 (50 mL) and chromatographed over a column of neutral Al2O3 with elution by hexane, hexane + benzen, benzene, benzene +chloroform, chloroform and chloroform+ etanol, in different ratios. The volume of each fraction was 100 mL. The separation and isolation process was carried out using column (silicagel) and thin layer chromatographic (TLC) methods. Structure elucidation of thepurified compounds were based on IR, UV, 1H and 13C-NMR data, in comparison with those reported in theprevious literatures. The isolated compounds from the aceton extracts of P. umbrosa were identified as esculetin 2.5%, scopoletin 4.5%, and umbelliferon 3.5%.

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Section: Resultsmentioning

confidence: 99%

Isolation and Characterization of Phytochemicals of Pastinaca Umbrosa

Mammadova

Serkerov

2022

JCPRM

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“…The content of dietary fiber in parsnip is 30% of the dry matter, composed mainly by neutral sugars (18%), pectic compounds (10%) and Klason lignin (1.92%). Klason lignin represents the insoluble residue portion left after removing the ash by acid hydrolysis of the plant tissue [54,55].…”

Section: Parsnipmentioning

confidence: 99%

“…The phytochemicals in parsnip root have been shown to possess a wide spectrum of pharmacological properties, which made them useful in tackling conditions such as Root Vegetables: Biology, Nutritional Value and Health Implications DOI: http://dx.doi.org/10.5772/intechopen.106240 neurological, respiratory, gastrointestinal, liver, skin, heart and urogenital disorders [54]. In vitro cell culture experiments have also shown cytotoxic effects of parsnip phytochemicals on cancer cell lines.…”

Section: Parsnipmentioning

confidence: 99%

Root Vegetables: Biology, Nutritional Value and Health Implications

Ahmadi¹,

Hulea²,

Peţ³

2023

Advances in Root Vegetables Research

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Plants served as main staple for humanity since time immemorial. Plant roots science is a fascinating domain that offers a window to the complex world of plants-microorganisms relationship. Plant roots were used throughout human history both as a food source particularly in times of food scarcity as well as for medicinal purposes aid in the treatment of various human disorders. Root vegetables are excellent sources of fiber and antioxidants and are low in calories and lipids—being indispensable in human diet. There is an increasing interest in the biochemical processes occurring in the rhizosphere between root tissues and the bacterial/fungal colonizers especially in soils where there is a deficiency in minerals such as iron, phosphorus and selenium or there is higher load of toxic metals such as aluminum, cadmium, nickel and lead. That interest stems from the need to improve crop yields in hostile environmental conditions such as drought and low nutrient availability in soils. In this chapter, we will focus on the typical edible plant roots as well as bulbs (are not proper roots) looking at their nutrient content as well as their use as health enhancers.

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“…Parsnip (Pastinaca sativa L.) is a plant species that is indigenous to Europe and Asia [103], and is also found growing in South Kazakhstan [104].…”

Section: Pastinaca Sativa L Seler Family -Apiaceaementioning

confidence: 99%

Medicinal Plants of the Flora of Kazakhstan Used in the Treatment of Skin Diseases

Berganayeva¹,

Kudaibergenova²,

Litvinenko³

et al. 2023

Preprint

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According to the eminent scholar, philosopher, and physician Avicenna, "the doctor has three tools: the word, the plant, the knife." The plant kingdom is recognized as humanity's earliest and most ancient healing source, employed for the management and prevention of illnesses. Tracing back through history, the most ancient documented proof of plants' utilization in medicine dates back to a Sumerian clay slab discovered in Nagpur roughly 5000 years ago. This artifact included a compilation of twelve medicinal recipes that involved over 250 diverse plant species. Sumerian healers extracted powders and infusions from plant roots and stems, while also crediting healing properties to pears and figs. Additionally, they utilized dried and ground young shoots of willow and plum trees, pine and fir needles as a component in compresses and poultices. Often, powders from animal and mineral sources were blended with those extracted from dried and crushed plants. Notably, in addition to water, wine and beer served as solvents. Thus, at least 80 centuries ago, people utilized the most uncomplicated medicinal plant-based preparations for treatment [1]. The "Pen T'Sao," an ancient Chinese text on roots and herbs, authored by Emperor Shen Nung approximately 2500 BC, contains descriptions of 900 medicaments (comprising dried components of medicinal plants). Several of these substances are still in use today, including Rhei rhisoma, camphor, Theae folium, Podophyllum, great yellow gentian, ginseng, datura, cinnamon bark, and ephedra [2]. Regarding Kazakh folk medicine, an area that has yet to be fully explicated and substantiated, it can be stated that the traditional medicinal knowledge of the Kazakh people transcends the mere treatment of ailments and rests on robust theoretical underpinnings. Oteiboydak Tleukabyluly (1388-1478), an astute healer and prominent figure in Kazakh folk medicine during the 15th century, comprehensively explicated the secrets of the healing art in his medical and ethnographic work "Medical Narrative," which he composed between 1466 and 1473 at the behest of az-Zhanibek Khan, who held him in high esteem as a great healer. This medical encyclopedia delineates the functions of various organs of the human body and provides a catalogue of the primary diseases associated with them. Furthermore, it includes a meticulous description of the methods used in traditional medicine at present, such as setting bones, listening to the pulse, and incantations. Through practical experimentation and experimentation conducted in the steppe laboratory, the healer formulated a total of 1,108 different medicinal compounds, of which 858 were derived from medicinal plants, 318 were extracted from animal organs, and roughly 60 were sourced from metals. The moniker "Teacher without a teacher" was bestowed on Oteiboydak Tleukabylov, who discovered methods for treating 1,050 different diseases [3]. At present, the employment of phytotherapy has gained widespread acceptance on a global scale. According to the World Health Organization's (WHO) global review of national policies concerning traditional, complementary, and alternative medicine, as well as the regulation of herbal medicines, there is an evident growth in the European and Asian market for herbal medicines [4]. Kazakhstan boasts a natural flora of over 6,000 plant species [5]. The exact number of medicinal plant species present in Kazakhstan remains uncertain, as the list continues to expand annually. More than 150 plant species have been employed in both official and folk medicine for various ailments. This review focuses on a selection of medicinal plants growing within the territory of the Republic of Kazakhstan that have traditionally been used to alleviate skin diseases. In conducting this study (2010-2023), emphasis was placed on the plants' phytochemical composition, with a particular focus on the principal components responsible for their therapeutic effects against inflammatory skin conditions such as dermatitis, atopic dermatitis, and eczema.

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Review of Pharmacological Properties and Chemical Constituents of Pastinaca sativa

Cited by 28 publications

References 34 publications

Isolation and Characterization of Phytochemicals of Pastinaca Umbrosa

Isolation and Characterization of Phytochemicals of Pastinaca Umbrosa

Root Vegetables: Biology, Nutritional Value and Health Implications

Medicinal Plants of the Flora of Kazakhstan Used in the Treatment of Skin Diseases

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