Review of Pineal Anlage Tumor With Divergent Histology

Berns, Stephen; Pearl, Gary S.

doi:10.5858/2006-130-1233-ropatw

Cited by 20 publications

(2 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…PAT has been described mainly in single case reports 1,2,4,[10][11][12][13][14][15][16][17][18] (see also Supporting Table S4). PAT occurs primarily in children under 2 years of age, and causes symptoms due to mass effect and hydrocephalus.…”

Section: Discussionmentioning

confidence: 99%

Two cases of pineal anlage tumor with molecular analysis

Scherpelz

Crotty

Paulson

et al. 2022

Pediatric Blood & Cancer

View full text Add to dashboard Cite

Pineal anlage tumor is a rare pediatric tumor with clinical and histological features overlapping with pineoblastoma. Two patients with pineal anlage tumor, a 13-month-old female and an 11-month-old male, underwent subtotal resection, high-dose chemotherapy with autologous stem cell rescue, and radiation. Neither had tumor progression 50 months after diagnosis. The tumors underwent next-generation sequencing on a panel of 340 genes. Chromosomal copy gains and losses were present and differed between the tumors. No mutations or amplifications, including none specific to pineoblastoma, were identified.

show abstract

Section: Discussionmentioning

confidence: 99%

Two cases of pineal anlage tumor with molecular analysis

Scherpelz

Crotty

Paulson

et al. 2022

Pediatric Blood & Cancer

View full text Add to dashboard Cite

show abstract

“…Silver staining highlights the scant cytoplasm and few cellular processes. Melanin production as well as cartilaginous and rhabdomyoblastic differentiation are encountered in pineal anlage tumors (4,23).…”

Section: Discussionmentioning

confidence: 99%

Pineoblastomas in Pediatric Patients: A Single Institutional Experience

Lăpădat¹

2022

JMRO

View full text Add to dashboard Cite

Pineoblastomas are rare, malignant pineal parenchymal tumors encountered predominantly in pediatric patients. They are distinct from primitive neuroectodermal tumors (PNET) at other sites in that they exhibit photosensory differentiation including Flexner–Wintersteiner rosettes and fleu-rettes. Diagnosis can be challenging since they share morphologic and immunohistochemical fea-tures with other embryonal tumors and the developing pineal gland. Pineal anlage tumor is a rare variant of pineoblastoma defined by divergent neuroepithelial and ectomesenchymal differentia-tion without an endodermal component. To date the five published cases of anlage tumors be-haved aggressively. We describe a case series which includes one patient with pineal anlage tu-mor and the clinical, radiological and pathological characteristics of pediatric pineoblastomas.

show abstract

Pineal Tumors

Lacruz

2023

Central Nervous System Tumors

View full text Add to dashboard Cite

Review of Pineal Anlage Tumor With Divergent Histology

Cited by 20 publications

References 6 publications

Two cases of pineal anlage tumor with molecular analysis

Two cases of pineal anlage tumor with molecular analysis

Pineoblastomas in Pediatric Patients: A Single Institutional Experience

Pineal Tumors

Contact Info

Product

Resources

About