Review of prophylactic prescribing of antibiotics during the management of fractured mandibles

Chaudhry, Hiba; Hennedige, Anusha; Patel, Manu

doi:10.1016/j.surge.2020.12.009

Cited by 2 publications

(5 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The first systematic review by Andreasen et al, in 2006, already demonstrated that 24 h of antibiotic prophylaxis suffices as antimicrobial prophylaxis in all maxillofacial fractures [6]. These findings were confirmed in all subsequent systematic reviews [1,3,7,[11][12][13][14][15][16][17].…”

Section: Discrepancy Between Guidelines and Clinical Practicementioning

confidence: 77%

“…One more study was excluded because it unclearly described which fractures were treated surgically and which were treated non-surgically [51]. Previously published systematic reviews included these studies [1,3,7,[12][13][14]16,17] and even performed a meta-analysis [1,7,14]. In our opinion, the strict inclusion criteria enhanced the strength of our study and led to a more appropriate representation of available evidence.…”

Section: Clinical Heterogeneity and The Limited Number Of High-qualit...mentioning

confidence: 96%

“…To the best of our knowledge, 11 systematic reviews on systemic antibiotic prophylaxis in maxillofacial fracture treatment were published over the past 15 years [1,3,6,7,[11][12][13][14][15][16][17]. The first systematic review by Andreasen et al, in 2006, already demonstrated that 24 h of antibiotic prophylaxis suffices as antimicrobial prophylaxis in all maxillofacial fractures [6].…”

Section: Discrepancy Between Guidelines and Clinical Practicementioning

confidence: 99%

“…However, these recommendations are mainly based on a handful of clinical studies and uncertainty persists regarding the optimal antibiotic regimen for infection prevention. Previously published systematic reviews often included studies with a significant risk of bias, leading to a misrepresentation of the currently available evidence [1,3,6,7,[11][12][13][14][15][16][17]. For these reasons, and on a worldwide scale, heterogeneity in infection prevention protocols still exist.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Systemic Antibiotic Prophylaxis in Maxillofacial Trauma: A Scoping Review and Critical Appraisal

et al. 2022

View full text Add to dashboard Cite

Infection after maxillofacial trauma remains an important complication, with a significant socio-economic impact. While consensus exists that systemic antibiotic prophylaxis reduces the risk of infection in the management of maxillofacial fractures, the type, and duration remain controversial. Therefore, the purpose of this scoping review was to provide an overview of the current evidence that supports the use of prophylactic antibiotics in the treatment of maxillofacial fractures. A comprehensive literature search on 1 January 2022, in PubMed, Web of Science, Embase, and Cochrane, revealed 16 articles. Most studies focused on the duration of systemic antibiotic prophylaxis and compared a one-day to a five-day regimen. Included studies showed considerable variability in design and research aims, which rendered them difficult to compare. Furthermore, a variety of antibiotic regimens were used, and most studies had a short follow-up period and unclear outcome parameters. This scoping review demonstrates the lack of well-constructed studies investigating the type and duration of systemic antibiotic prophylaxis in the treatment of maxillofacial trauma. Based on the included articles, prolonging antibiotic prophylaxis over 24 h for surgically treated fractures does not appear to be beneficial. Furthermore, there is no evidence for its use in conservatively treated fractures. These results should be interpreted with caution since all included studies had limitations.

show abstract

Section: Discrepancy Between Guidelines and Clinical Practicementioning

confidence: 77%

Section: Clinical Heterogeneity and The Limited Number Of High-qualit...mentioning

confidence: 96%

Section: Discrepancy Between Guidelines and Clinical Practicementioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Systemic Antibiotic Prophylaxis in Maxillofacial Trauma: A Scoping Review and Critical Appraisal

et al. 2022

View full text Add to dashboard Cite

show abstract

“…The latter was characterized by the fact that on the 3-4th day after the injury (with early purulent complications) there was an increase in the studied parameters by 1.5-2 times, and similarly on the 7-8th day of treatment -with late purulent complications (post-traumatic osteomyelitis). 1,[6][7][8][9][10][11] The normalization of these indicators in patients with developed complications occurred only after the complete elimination of inflammatory phenomena in the bone tissue and peri-maxillary soft tissues. For patients with post-traumatic complications, it was characteristic that on the 3-4th day after the injury (with early purulent complications) there was an increase in the studied parameters by 1.5-2 times, and similarly on the 7-8th day of treatment -with late purulent complications (post-traumatic osteomyelitis).…”

Section: Resultsmentioning

confidence: 99%

Modern Methods of Patients’ Examination with Traumatic Jaw Injuries

Tymofieiev

Havlytiuk

Ripa

et al. 2022

J. Diagn. Treat. Oral Maxillofac. Pathol.

View full text Add to dashboard Cite

Purpose: To determine the possibility of using cytological methods for examining prints taken from the mucous membrane of the alveolar process of a jaw in the area of the bone injury, to determine the effectiveness of the treatment of patients with jaw fractures. Materials and Methods: We examined 43 patients with jaw fractures. All patients were divided into the following observation groups: group 1 – 19 patients with fractures of the maxilla; group 2 – 24 patients with fractures of the mandible. As a control group served 27 practically healthy people. Results and Discussion: For patients with post-traumatic complications, it was characteristic that on the 3-4th day after the injury (with early purulent complications) there was an increase in the studied parameters by 1.5-2 times, and similarly on the 7-8th day of treatment – with late purulent complications (post-traumatic osteomyelitis). The normalization of these indicators in patients with developed complications occurred only after the complete elimination of inflammatory phenomena both in the bone tissue and soft tissues. Conclusions: The study of cytological and cytochemical parameters in prints taken from the mucous membrane of the alveolar process in the area of the fracture allows both to determine the effectiveness of the treatment and to predict the course of the disease.

show abstract

Review of prophylactic prescribing of antibiotics during the management of fractured mandibles

Cited by 2 publications

References 25 publications

Systemic Antibiotic Prophylaxis in Maxillofacial Trauma: A Scoping Review and Critical Appraisal

Systemic Antibiotic Prophylaxis in Maxillofacial Trauma: A Scoping Review and Critical Appraisal

Modern Methods of Patients’ Examination with Traumatic Jaw Injuries

Contact Info

Product

Resources

About