Background.
The elderly population is expanding world-wide but is
underrepresented in clinical trials. We sought to assess the safety of
robotic gynecologic surgery in an elderly cohort and to identify factors
associated with unfavorable outcomes.
Methods.
All patients ≥ 65 years who underwent a robotically assisted
procedure at a single institution between May 2007 to December 2016 were
divided into three age groups: 65–74 (Group 1); 75–84 (Group
2); ≥ 85 (Group 3). Perioperative outcomes were recorded in patients
who did not require conversion to laparotomy. We compared clinical variables
among groups and performed multivariate logistic regression to detect
variables associated with major complications (≥ Grade 3) or 90-day
mortality.
Results.
We retrospectively identified 982 cases: 685 in Group 1; 249 in Group
2; 48 in Group 3. Median age = 71 years. Median BMI = 28.9. Malignancy was
documented in 72.8% of cases; the majority were endometrial cancer (61.8%).
Thirty-four patients (3.5%) were read-mitted within 30 days. Seventy-seven
(7.8%) had a postoperative complication, and 23 (2.3%) had a major
complication. Ninety-day mortality was 0.5%. There was significant
difference between groups with respect to body mass index
(P = 0.026), ECOG PS (P ≤
0.001), > 5 comorbidities (P = 0.005), hospital stay
(P < 0.001), major complications
(P = 0.001), and 90-day mortality (P
< 0.001). On multivariable logistic regression, age ≥ 85 years
was associated with major complications. Body mass index, age ≥ 85
years, and major complications were significantly associated with 90-day
mortality.
Conclusions.
Robotic-assisted surgery appears to be safe in an elderly cohort. The
incidence of overall and major complications is consistent with those
reported in the literature. Patients ≥ 85 years old appear to be at
higher risk of unfavorable outcomes.