Review of synthetic mesh-related complications in pelvic floor reconstructive surgery

Bako, Abdulmalik; Dhar, Ruchika

doi:10.1007/s00192-008-0717-5

Cited by 106 publications

(63 citation statements)

References 52 publications

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“…Despite improvement in the knowledge of pelvic anatomy and advances in surgical techniques, the success rates of traditional pelvic reconstructive surgical procedures are variable and sometimes disappointing with an overall recurrence rate of 30% [1][2][3].…”

Section: Introductionmentioning

confidence: 99%

New approach in vaginal prolapse repair: mini-invasive surgery associated with application of platelet-rich fibrin

Gorlero¹,

Glorio²,

Lorenzi³

et al. 2012

Int Urogynecol J

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Section: Introductionmentioning

confidence: 99%

New approach in vaginal prolapse repair: mini-invasive surgery associated with application of platelet-rich fibrin

Gorlero¹,

Glorio²,

Lorenzi³

et al. 2012

Int Urogynecol J

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“…Simultaneously there is increasing evidence of long term mesh-related complications described by Bako and Dhar (2009). These complications could have significant impact on the quality of life of those patients Ridgeway et al (2008).…”

Section: Discussionmentioning

confidence: 99%

“…However, these new surgical procedure have brought with them new mesh-related complications such as erosion, pain syndrome, etc. as described by Bako and Dhar (2009). Some of these complications -erosion, shrinkage and abnormal pain -can result from abnormal postoperative healing due to surgical site infection.…”

Section: Introductionmentioning

confidence: 99%

A Comparison of the Incidence of Early Postoperative Infections between Patients Using Synthetic Mesh and Those Undergoing Traditional Pelvic Reconstructive Surgical Procedures

et al. 2013

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R e c e i ve d Ju ly 2 , 2 0 1 2 ; A c c e p t e d A p r i l 8 , 2 0 1 3 . Key words: Febrile morbidity -Pelvic organ prolapse -Postoperative infectionsSepsis -Synthetic polypropylene meshAbstract: New mesh-related complications such as erosion, etc., can result from abnormal postoperative healing due to surgical site infection. The aim of our study was to compare systemic inflammatory responses and the incidence of early infectious complications after reconstructive surgery using synthetic mesh and after traditional vaginal wall repair. In this prospective observational study 99 women with symptomatic pelvic organ prolapse were included; 55 women underwent traditional repair and 44 repair using mesh. After the procedure infectious complications were monitored. The patients who underwent reconstructive Republic, and surgery using mesh material were more likely to have febrile morbidity in the postoperative period than the patients who had been treated with traditional repair (p=0.031); there was a higher incidence of combination febrile morbidity with elevated C-reactive protein (CRP) > 50 mg/l; p=0.046, and a higher incidence of CRP increase over 30 mg/l; p=0.005. Reconstructive procedures using synthetic mesh are accompanied by a higher incidence of early post-operative infectious complications. This study was supported by the Grant Agency of the Ministry of Health of the Czech IntroductionPelvic organ prolapse is a common problem affecting up to 50% of parous women (Subak et al., 2001). Not all of them are symptomatic (Olsen et al., 1997;Baessler and Maher, 2006), and the risk of requiring surgery for prolapse is 11-12% in women reaching 79 years of age (Olsen et al., 1997). For a long time traditional pelvic reconstruction surgical procedures were the only ones available. The longterm efficiency of those procedures varied, and re-operation rates of nearly 30% have been reported by Olsen et al. (1997), with a risk of recurrence of up to 45% according to Valaitis and Stanton (1994) and Kohli et al. (1998). This may be one of the reasons why synthetic meshes were introduced to pelvic reconstructive surgery. However, these new surgical procedure have brought with them new mesh-related complications such as erosion, pain syndrome, etc. as described by Bako and Dhar (2009). Some of these complications -erosion, shrinkage and abnormal pain -can result from abnormal postoperative healing due to surgical site infection.The vagina contains more microorganisms than any other site in the body except the bowel (Lamont and Haynes, 2008). Surgical procedures resulting in the opening of the vagina will result in contamination of normally sterile sites by bacteria that are normally resident in the vagina. Infection and inflammation depends on a mixture of surgical and host-related factors. When mesh material is used this decreases the size of the bacterial inoculum, which can induce postoperative infection.The aim of our study was to compare immediate inflammatory reaction and the incidence of infectious complications afte...

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“…However, the advent of synthetic mesh and "mesh kits" with synthetic arm extensions into the ischiorectal fossa, transobturator foramen, and sacrospinous ligament for prolapse repair has given way to a new set of pain syndromes. De novo dyspareunia rate of up to 38 % has been reported following transvaginal mesh placement [ 64 ]. Withagen et al attempted to identify risk factors for mesh complications and prospectively studied 294 women treated with tension-free trocar-guided mesh kits for POP.…”

Section: Painmentioning

confidence: 99%

Pelvic Organ Prolapse: Planning for Surgery—Indications, Decision, Special Instruments, and Controversies

Lee

2014

Minimally Invasive Therapy for Urinary Incontinence and Pelvic Organ Prolapse

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Review of synthetic mesh-related complications in pelvic floor reconstructive surgery

Cited by 106 publications

References 52 publications

New approach in vaginal prolapse repair: mini-invasive surgery associated with application of platelet-rich fibrin

New approach in vaginal prolapse repair: mini-invasive surgery associated with application of platelet-rich fibrin

A Comparison of the Incidence of Early Postoperative Infections between Patients Using Synthetic Mesh and Those Undergoing Traditional Pelvic Reconstructive Surgical Procedures

Pelvic Organ Prolapse: Planning for Surgery—Indications, Decision, Special Instruments, and Controversies

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