Review on Analytical Method Development and Validation by HPLC/Lc-MS of Selected Anti-Cancer Drugs

Reddy, M. Rajavardhan

doi:10.20959/wjpps20174-8876

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Dasatinib Was Approved For Medical Use In the United1

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2023

2024

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Cited by 2 publications

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“…States and in the European Union in 2006 [3]. It is on the World Health Organization's List of Essential Medicines.…”

Section: Dasatinib Was Approved For Medical Use In the Unitedmentioning

confidence: 99%

Overall review on analytical method development and validation of Dasatinib

Nuli¹,

Rekulapally²

2023

Int J Pharm Chem

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In this review article determines the different analytical methods for the quantitative establishment of Dasatinib by using HPLC, HPLCMS, HPLC-UV, LC-MS/MS. Pharmaceutical analytical method development of Dasatinib requires valid analytical procedures for quantitative and qualitative analysis in Pharmaceuticals dosage formulations and human serum. This assessment explains that the superiority of the HPLC/LC-MS methods reviewed is based on the quantitative analysis of drugs in formulations, (API), biological fluids such as serum and plasma.

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“…States and in the European Union in 2006 [3]. It is on the World Health Organization's List of Essential Medicines.…”

Section: Dasatinib Was Approved For Medical Use In the Unitedmentioning

confidence: 99%

Overall review on analytical method development and validation of Dasatinib

Nuli¹,

Rekulapally²

2023

Int J Pharm Chem

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An Overview of Analytical and Bioanalytical Techniques for the determination of Tyrosine Kinase Inhibitors

Gowthami,

2024

RJPT

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Tyrosine KIs have become a targeted drug therapy for different malignancies. Over the past ten years, kinase inhibitors, including monoclonal antibodies and small-molecule TKIs targeted at kinases, have become a significant class of chemotherapeutic agents. A number of studies documenting the design, usage and validation of bioanalytical methods for TCKIs have been published as a result of the rising need for bioanalytical approaches to both qualitatively and quantitatively study such compounds. Many biomatrices, including blood, cerebrospinal fluid, urine, tissue, and even liver microsomes, can be used to quantify TCKIs. The majority of papers explain the technological framework of analytical methods that can do this. In recent times, there has also been an increase in interest in the discovery of intermediates and biotransformation mechanisms for novel TCKIs. We give a summary of TCKI bioanalytical techniques.

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Review on Analytical Method Development and Validation by HPLC/Lc-MS of Selected Anti-Cancer Drugs

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Cited by 2 publications

References 11 publications

Overall review on analytical method development and validation of Dasatinib

Overall review on analytical method development and validation of Dasatinib

An Overview of Analytical and Bioanalytical Techniques for the determination of Tyrosine Kinase Inhibitors

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