Review on Chemistry and Bioactivities of Secondary Metabolites from Some Medicinal Plants and Microbes of Bangladesh

Rashid, Mohammad A.; Haque, Mohammad Rashedul; Sikder, Al Amin; Chowdhury, Abu Asad; Rahman, Mohammad Shafiqur; Hasan, Choudhury Mahmood

doi:10.3329/bpj.v17i1.22307

Cited by 12 publications

(10 citation statements)

References 53 publications

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“…The decrease in the wetness of feces and the frequency of defecation as well as the decrease in the intensity and frequency of body squirming observed, proved the potent antidiarrhoeal and analgesic activities of P. neriifolius leaves which might be due to the inhibition of prostaglandins biosynthesis. Previous phytochemical screenings of the plant extract revealed the presence of terpenoids, steroids, flavanoids, polyphenolics and fats (Zhen et al, 1993;Rashid et al, 2014). Many plants exhibited analgesic and antidiarrheal activities due to the presence of saponins, terpenoids, steroids and flavonoids (Owleye et al, 2005).…”

Section: Resultsmentioning

confidence: 99%

Analgesic and Antidiarrheal Activities of Leaf of Podocarpus neriifolius D. Don

Razan

Tahia²,

Hossain

et al. 2016

Bangla Pharma J

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The methanol extract of leaf of Podocarpus neriifolius D. Don exhibited in vivo peripheral analgesic and antidiarrheal activities in Swiss Albino mice. In the peripheral analgesic activity assay, the methanolic extract showed 50.00 ± 8.57% and 70.25 ± 1.18% inhibition of acetic acid-induced writhing at 200 and 400 mg/kg body weight, respectively. In addition, the extract also revealed a dose dependant inhibition of castor oilinduced diarrhea with 43.77 ± 3.13% and 56.23 ± 6.49% inhibition of feces at 200 and 400 mg/kg body weight, respectively.

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Section: Resultsmentioning

confidence: 99%

Analgesic and Antidiarrheal Activities of Leaf of Podocarpus neriifolius D. Don

Razan

Tahia²,

Hossain

et al. 2016

Bangla Pharma J

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“…According to World Health Organization (WHO), 80% of the population, mostly in developing countries still relies on plant-based medicines for their primary health care (Ghani, 2003;Ezuruike and Prieto, 2014;Samsam and Moatar, 1991). Plants and microbes produce a diverse range of bioactive molecules, making them a rich source of different types of medicines (Cragg and Newman, 2013;Rashid et al, 2014). In modern medicines, they occupy a very significant place as raw materials for important therapeutic agents (Dias et al, 2012).…”

Section: Introductionmentioning

confidence: 99%

Analgesic, Anti-diarrheal, Anti-depressant, Membrane Stabilizing and Cytotoxic Activities of Bridelia verrucosa Haines

et al. 2019

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The present study was aimed for the evaluation of analgesic, anti-diarrheal and anti-depressant activities of methanol crude extract of Bridelia verrucosa leaves in Swiss albino mice. The analgesic activity was assessed by formalin-induced paw licking method, where the crude extract of B. verrucosa (400 mg/kg, b.w.) exhibited 54.55% reduction of licking response in mice as compared to 69.09% reduction exhibited by standard acetylsalicylic acid. In the castor oil-induced diarrhea in mice, the plant extract at the dose of 400 mg/kg, b.w., demonstrated 57.67% reduction of diarrheal feces in mice. The antidepressant activity of the plant extract was evaluated through phenobarbitone-Na induced sleeping time test. The methanol extract of B. verrucosa and its different Kupchan fractions were also subjected to screenings for membrane stabilizing and cytotoxic activities using acetylsalicylic acid and vincristine sulphate as standard, respectively. Bangladesh Pharmaceutical Journal 22(1): 50-55, 2019

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“…The total medicinal plant market of Bangladesh is equivalent to US$ 14 billion each year. 1 Blumea lacera (Burn.f.) DC.…”

Section: Introductionmentioning

confidence: 99%

Preliminary phytochemical screenings and Pharmacological activities of Blumea lacera (Burn.f.) DC.

Khair

Ibrahim

Ahsan

et al. 2015

Dhaka Univ. J. Pharm. Sci

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The methanol extract of the whole plant of Blumea lacera (Burn.f.) DC. (BLME) has been subjected to preliminary screenings for phytoconstituents and antipyretic, analgesic and anti-inflammatory activities. Antipyretic activity was assessed by the yeast-induced hyperthermia in mice. The analgesic property was evaluated by formalin-induced writhing test. Acetyl salicylic acid (ASA) was used as standard for in-vitro anti-inflammatory activity test. In yeast-induced pyrexia, the crude extract demonstrated a significant (p=0.05) reduction in body temperature of mice after elevation by the administration of yeast. These effects were pronounced at the 2nd and 3rd h of post-treatment with the extract. BLME exhibited a dose-dependent analgesic activity with 39.13% and 56.52% protection at 200-and 400-mg/kg, b.w., respectively as compared to 76.09% revealed by the standard diclofenac sodium. In the anti-inflammatory test, the crude extract at 400 ?g/ml displayed 62.40% inhibition of protein denaturation whereas standard acetyl salicylic acid exhibited 76.74% inhibition. Results of the preliminary phytochemical screenings demonstrated the presence of alkaloids, flavonoids and triterpenoids in the extract. DOI: http://dx.doi.org/10.3329/dujps.v13i1.21863 Dhaka Univ. J. Pharm. Sci. 13(1): 69-73, 2014 (June)

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Review on Chemistry and Bioactivities of Secondary Metabolites from Some Medicinal Plants and Microbes of Bangladesh

Cited by 12 publications

References 53 publications

Analgesic and Antidiarrheal Activities of Leaf of Podocarpus neriifolius D. Don

Analgesic and Antidiarrheal Activities of Leaf of Podocarpus neriifolius D. Don

Analgesic, Anti-diarrheal, Anti-depressant, Membrane Stabilizing and Cytotoxic Activities of Bridelia verrucosa Haines

Preliminary phytochemical screenings and Pharmacological activities of Blumea lacera (Burn.f.) DC.

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