Review on Clinical Diseases Caused by Klebsiella

Sathyavathy, K.; Madhusudhan, B. Kiran

doi:10.9734/jpri/2020/v32i2130745

Cited by 8 publications

(6 citation statements)

References 13 publications

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“…The DDST lacks sensitivity because of the problem in optimal disc space and storage of Clavulanicacid containing discs. According to CLSI guidelines, PCDDT is recommended for confirmatory method to detect ESBL producing Klebsiella species [26,27,11]. The limitation of this study was that PCR were not performed due to cost factor.…”

Section: Discussionmentioning

confidence: 99%

“…Various clinical samples such as sputum, urine, wound swab/pus and blood received in the central diagnostic laboratory from General surgical wards were processed in microbiology section. Samples were then subjected to microscopy, bacteriological culture, biochemical identification and Antimicrobial susceptibility testing [11]. The specimens of pus and wound exudates were collected in disposable sterile swab stick/sterile syringe.…”

Section: Methodsmentioning

confidence: 99%

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Isolation, Identification, Speciation and Antibiotic Susceptibility Pattern of Klebsiella Species among Various Clinical Samples at Tertiary Care Hospital

Sathyavathy

Madhusudhan

2021

JPRI

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To isolate, identify and speciate Klebsiella from various clinical samples and their Antimicrobial susceptibility pattern at tertiary care hospital, Chennai. Out of this 76 ESBL producing Klebsiella pneumoniae, 64(84%) were positive by Double Disc Synergy Test (DDST), 71(93%) by phenotypic confirmatory disc diffusion test (PCDDT) and 69(90.7%) by Etest strip method. Sensitivity was found to be maximum (93%) by PCDDT method, compared to other phenotypic methods such as DDST and Etest strip method. The Present study also highlights the need for the continued monitoring of Antimicrobial susceptibility patterns of important bacterial pathogens, so that rational antibiotic policies can be formulated.

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Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Isolation, Identification, Speciation and Antibiotic Susceptibility Pattern of Klebsiella Species among Various Clinical Samples at Tertiary Care Hospital

Sathyavathy

Madhusudhan

2021

JPRI

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“…The antimicrobial activities of the newly synthesized templated nano sized titania has been verified against common human pathogens like K. neomonia and H. influenza. Thus produced reactive oxygen species (ROS) during the exposure of the catalyst's surface to sunlight might disorder bacterial, fungus, and virus's gene multiplication including the destruction of their cell membrane [19].…”

Section: Introductionmentioning

confidence: 99%

Extensive studies on the Electrochemical, Photocatalytic and Antimicrobial Applications of Bio assisted Nano Titania

Saikumari¹,

Sudhakhar

2023

Preprint

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In recent days synthesis and structuring of intelligent nano materials investigated and reported has developed critical scientific ideas to the greater extent. The excellent thermal, optical and electrical properties along with its resistant to corrosion, wear, oxidation and erosion made it unique for sustainable environmental applications. Here nano structured Titanium di oxide particles synthesized from its precursor via template assisted sol-gel technique have been verified as corrosion inhibitor of brass alloy in acid medium along with its photo catalytic and anti-microbial applications. The physico-chemical parameters of the synthesized nano materials were studied using XRD, FT-IR, UV-DRS, SEM, TEM and BET analytical techniques and revealed the impact of tea leaf extract as a template in producing a nano catalyst NTG about 14 nm in size with tailored structural, optical and morphological characteristics. The rate of corrosion of a brass strip in acid medium is verified by weight loss method and the inhibitor efficiency increased with the increase in concentration of the nano catalyst. The catalytic activity is proved against the photo degradation of a toxic melamine, a trimer of cyanamide. The synthesized nano catalyst showed excellent antimicrobial properties proven against the growth of K. pneumonia and H. influenza.

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“…Klebsiella pneumonia (K. pneumonia) is a rod-shaped, lactose fermenting, Gramnegative bacterium commonly found in the skin, mouth, and intestinal tract [3]. Infection can lead to pneumonia, wound infection, meningitis, urinary tract infection, and septicemia.…”

Section: Introductionmentioning

confidence: 99%

The Antimicrobial Properties of Nanotitania Extract and Its Role in Inhibiting the Growth of Klebsiella pneumonia and Haemophilus influenza

et al. 2021

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Titanium dioxide (TiO2) is an antimicrobial agent which is considered of potential value in inhibiting the growth of multiple bacteria. Klebsiella pneumonia and Haemophilus influenza are two of the most common respiratory infection pathogens, and are the most. Klebsiella pneumonia causes fatal meningitis, while Haemophilus influenza causes mortality even in younger patients. Both are associated with bacteremia and mortality. The purpose of this study was to test a new antibacterial material, namely nanotitania extract combined with 0.03% silver that was developed at Universiti Malaysia Sabah (UMS) and tested against K. pneumonia and H. influenza. The nanoparticles were synthesized through a modified hydrothermal process, combined with molten salt and proven to have excellent crystallinity, with the band-gap energy falling in the visible light spectrum. The nanoparticle extract was tested using a macro-dilutional method, which involved combining it with 0.03% silver solution during the process of nanoparticle synthesis and then introducing it to the bacteria. A positive control containing the bacteria minus the nanoparticles extract was also prepared. 25 mg/mL, 12.5 mg/mL, and 6.25 mg/mL concentrations of the samples were produced using the macro dilution method. After adding the bacteria to multiple concentrations of nanoparticle extract, the suspensions were incubated for 24 h at a temperature of 37 °C. The suspensions were then spread on Mueller-Hinton agar (K. pneumonia) and chocolate blood agar (H. influenza), where the growth of bacteria was observed after 24 h. Nanoparticle extract in combination with silver at 0.03% was proven to have potential as an antimicrobial agent as it was able to inhibit H. influenza at all concentrations. Furthermore, it was also shown to be capable of inhibiting K. pneumonia at concentrations of 25 mg/mL and 50 mg/mL. In conclusion, the nanoparticle extract, when tested using a macro-dilutional method, displayed antimicrobial properties which were proven effective against the growth of both K. pneumonia and H. influenza.

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Review on Clinical Diseases Caused by Klebsiella

Cited by 8 publications

References 13 publications

Isolation, Identification, Speciation and Antibiotic Susceptibility Pattern of Klebsiella Species among Various Clinical Samples at Tertiary Care Hospital

Isolation, Identification, Speciation and Antibiotic Susceptibility Pattern of Klebsiella Species among Various Clinical Samples at Tertiary Care Hospital

Extensive studies on the Electrochemical, Photocatalytic and Antimicrobial Applications of Bio assisted Nano Titania

The Antimicrobial Properties of Nanotitania Extract and Its Role in Inhibiting the Growth of Klebsiella pneumonia and Haemophilus influenza

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