Review on Darunaj-aqrabi (Doronicum hookeri C.B. Clarke): an Unexplored Medicinal Plant of Unani System of Medicine

Aleem, Mohd; Khan, Mohd. Imran; Usmani, Qamrul Islam; Ahmad, Altaf

doi:10.37591/joayush.v9i2.2108

Cited by 6 publications

(8 citation statements)

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“…The definition of Mizaj-e-advia (drug temperament) in Unani medicine is not only unique in defining the properties of drug substances in its own way, but it also stands the test of time by proving extremely useful in predicting drug actions on administration or topical application to humans [23][24][25] . The Mizaj of myrtle are mentioned in Unani literature are cold in first degree and dry in second degree [12-14, 26, 27] .…”

Section: Properties Of Myrtus Communis In Unani Medicine 61 Temperammentioning

confidence: 99%

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Therapeutic potential of Habb-ul-Aas (Myrtus communis Linn.) with Unani Perspective and Modern Pharmacology: A review

Aleem¹,

Shkir²

2021

J Pharmacogn Phytochem

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Myrtus communis Linn. (MC) is an important medicinal shrub being used in Unani Medicine for the treatment of diarrhoea, peptic ulcers, leucorrhoea, urethritis, haemorrhoids, conjunctivitis, palpitation, pulmonary and skin disease. This review provides data on the botany, phytochemical, Preclinical & Clinical Studies and Unani traditional uses of MC, with an aim to make update of the current information and obtain opportunities for further therapeutic potential. The information was obtained from scientific literature databases including PubMed, Research Gate, Google Scholar, Web of Science and Science Direct. Additional information was gathered from classical Unani text books, and published materials. MC are used traditionally for the treatment so many diseases. The Anti-inflammatory, Antimicrobial, Antioxidant, Hypoglycaemic, Anticancer, Analgesic, Antidiarrheal properties have been widely investigated. More than 50 active ingredients have been isolated from this plant including monoterpene, sesquiterpene, oxygenated sesquiterpenes, tannins and flavonoids. The present review verifies the real identity of Myrtle, summarizes its valuable description in Unani literature, and its medicinal efficacy in haemorrhoid, aphthous stomatitis, chronic rhinosinusitis, bacterial vaginosis (BV) and other disorders. Phytochemical and pharmacological studies and clinical investigations on the crude drug and isolated principles proved the multipotent action of Myrtle.

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Section: Properties Of Myrtus Communis In Unani Medicine 61 Temperammentioning

confidence: 99%

“…Most of the natural drugs used in Unani system are safe for human use, but some crude toxic drugs are first processed and purified in many ways before use to make them safer [24,28] . Some time it is used with other drugs to optimize the adverse effect.…”

Section: Adverse Effect and Correctivementioning

confidence: 99%

Therapeutic potential of Habb-ul-Aas (Myrtus communis Linn.) with Unani Perspective and Modern Pharmacology: A review

Aleem¹,

Shkir²

2021

J Pharmacogn Phytochem

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“…Besides, Doronicum species are used as natural depressants [5] . Nevertheless, rhizomes of certain Doronicum species are traditionally utilized as a constituent of tonics, exhilarant and act as a stomachic and dissolve trapped gases, while others are reported to avert giddiness caused during high attitude ascents [11] …”

Section: Introductionmentioning

confidence: 99%

“…[5] Nevertheless, rhizomes of certain Doronicum species are traditionally utilized as a constituent of tonics, exhilarant and act as a stomachic and dissolve trapped gases, while others are reported to avert giddiness caused during high attitude ascents. [11] Doronicum contains 26 species (and 4 subspecies) belonging in the Senecioneae, one of the largest and most complex tribes in the Asteraceae with 123 genera and 3200 species. [12] Although there have been studies examining the traditional uses and reporting the biological characteristics of a few Doronicum species such as antioxidant, anti-inflammatory, antimicrobial and antitumor activities, [11,[13][14][15] many of them are still understudied.…”

Section: Introductionmentioning

confidence: 99%

A Comparative Study of Chemical Profiling and Biological Effects ofDoronicum orientaleExtracts

Zengin

Mahomoodally

Sinan

et al. 2022

Chemistry & Biodiversity

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In this study, phytochemical and pharmacological screening of the aerial part and roots extracts from Doronicum orientale Hoffm. (Asteraceae) was carried out. Plant extracts were obtained using solvents of different polarity (hexane, ethyl acetate, ethanol, ethanol/water, water) for selection the most optimal solvent for the extraction of active compounds. For instance, the extracts yielded total phenolic and flavonoid contents in the range of 12.13–45.67 mg GAE/g and 0.75–12.44 mg QE/g, respectively, while the total antioxidant capacity of the extracts determined by the phosphomolybdenum assay ranged from 0.88–2.53 mmol TE/g. HPLC/MS/MS analysis revealed 5‐caffeoylquinic acid (2.52–337.05 μg/g) and 3,5‐dicaffeoylquinic acid (3.12–299.36 μg/g) to be the major components present in the investigated extracts. Antioxidant activity in terms of radical scavenging ability of the extracts ranged from 0.82–45.56 mg TE/g in DPPH assay and from 5.07–104.58 mg TE/g in ABTS assay. The tested extracts were found to inhibit acetylcholinesterase (aerial part: 0.50–2.33 mg GALAE/g; roots: 0.40–2.43 mg GALAE/g), while with the exception of the water extracts, the other extracts showed butyrylcholinesterase inhibition (aerial part: 2.46–5.02 mg GALAE/g; root: 2.93–4.17 mg GALAE/g). Overall, this study presented an interesting scope of this species in phytomedicine with preliminary data demonstrating some of the tested extracts to possess high bioactive contents, antioxidant potential and enzyme inhibitory activity. Thus, additional investigations are necessary to confirm their safety in herbal drug applications.

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“…Up to 65% of India's population and 80% in Africa depend on traditional medicine to help meet their health care needs 1 . The Unani Medicine, also referred to as Greco-Arabic medicine, Arabic medicine or Unani Tibb, is based on Hippocratic fourhumour theory; Dam (blood), Balgham (phlegm), Safra (yellow bile), and Sauda (black bile) 2,3 , and the four qualities of living human body states such as hararat (hot), barudat (cold), ratubat (moist) and yabusat (dry) 1 . Unani medicine uses medicinal products of plant, mineral, and animal origin but mostly plant origin drugs are used for therapeutic and preventive measures 4 .…”

Section: Introductionmentioning

confidence: 99%

Unani perspective on COVID-19 and the possible role of Tiryaq Wabai in its management: A Review

Aleem

Khan

Danish³

et al. 2021

J. Drug Delivery Ther.

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Science has uncovered much about SARS-CoV-2 and made extraordinary and unprecedented progress on the development of COVID-19 vaccines, but there is still great uncertainty as the pandemic continues to evolve. We are simply moving to a new phase of the pandemic. Tiryaq Wabai, is on the polyherbal medicine used for centuries by Unani doctors as preventative medicine in epidemics. It consists of three ingredients: Sibr (Aloe barbadensis), Zafran (Crocus sativus), and Mur-Makki (Commiphora myrrh). All the three ingredients of Tiryaq Wabai have various pharmacological activities like immunomodulatory, antitussive, expectorant, and antiviral activity which provide a strong basis for its prophylactic use for covid-19 infection. Further, research on this important prophylactic Unani formulation Tiryaq Wabai in Covid-19 is the need of the hour. Keywords: Tiryaq; Epidemic; Covid-19; Unani medicine

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Review on Darunaj-aqrabi (Doronicum hookeri C.B. Clarke): an Unexplored Medicinal Plant of Unani System of Medicine

Cited by 6 publications

References 0 publications

Therapeutic potential of Habb-ul-Aas (Myrtus communis Linn.) with Unani Perspective and Modern Pharmacology: A review

Therapeutic potential of Habb-ul-Aas (Myrtus communis Linn.) with Unani Perspective and Modern Pharmacology: A review

A Comparative Study of Chemical Profiling and Biological Effects ofDoronicum orientaleExtracts

Unani perspective on COVID-19 and the possible role of Tiryaq Wabai in its management: A Review

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