2020
DOI: 10.9734/ejnfs/2020/v12i730246
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Review on Ethno-botany, Virucidal Activity, Phytochemistry and Toxicology of Solanum genus: Potential Bio-resources for the Therapeutic Management of Covid-19

Abstract: Background and Aim: Condiment plants are not only a source of food, flavors or food additives but also antivirals. The aim of the present work consisted in compiling ethno-botanical, phytochemical, toxicological and biological activities literature data reported on some species of the Solanum genus, precisely their antiviral potential. Methodology: The literature review was based mainly on the usual databases such as PubMed, PubMed Central, Science Direct, SCIELO, DOAJ, Science alert and Google scholar.&… Show more

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Cited by 18 publications
(12 citation statements)
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“…The potential role of medicinal plants in the inhibition of the COVID-19 virus has been demonstrated by the molecular docking technique [4]. Also, the antiviral and immunomodulatory activity of medicinal plants is well established [25][26][27]. This strategy can be used to screen plant biodiversity (via molecular modelling) for anti-coronaviral potential.…”
Section: Resultsmentioning
confidence: 99%
“…The potential role of medicinal plants in the inhibition of the COVID-19 virus has been demonstrated by the molecular docking technique [4]. Also, the antiviral and immunomodulatory activity of medicinal plants is well established [25][26][27]. This strategy can be used to screen plant biodiversity (via molecular modelling) for anti-coronaviral potential.…”
Section: Resultsmentioning
confidence: 99%
“…The Solanum genus is probably one of the most important in the Solanaceae family with approximately 2000 species distributed worldwide. The members of this family have antiviral activity, making them candidates for novel antiviral molecules (12). One of the plants of this family used in Paraguayan folk medicine is Solanum sisymbriifolium (Solanaceae), a viscoid and very prickly erect shrub found in eastern Paraguay, known as ñuatıṕ ytâ in Guarani, the indigenous language still spoken in Paraguay, or sticky nightshade in English.…”
Section: Introductionmentioning
confidence: 99%
“…Currently, there are no specific treatments available for COVID-19 and several explorations relevant to the therapies of COVID-19 are becoming inadequate [12]. Consequently, other than vaccine development, academics and researchers have undertaken several strategies, by using on one hand traditional medicinal plants as possible alleviating drugs [13][14], and one the other hand by exploring in silico studies to pinpoint potential inhibitors from a set of secondary metabolites and other chemical compounds [15][16]. Nevertheless, it is worthy to mention that some studies have encountered the combinations of existing drug candidates (FDA approved drugs) involving anti -HIV drugs such as lopinavir/ritonavir, remdesivir, etc for therapeutic use against COVID-19 [17].…”
Section: Introductionmentioning
confidence: 99%