Review on Nitric Oxide, Carbon Monoxide and Antisense Based Therapy towards Treatment of Restenosis

Ramadugu, Prathibha; Alikatte, Kanaka Latha; Dhudipala, Narendar; Bommasane, Vikas

doi:10.4172/jbb.1000268

Cited by 1 publication

(1 citation statement)

References 56 publications

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“…Nitric oxide (NO) plays an important role in the regulation of intimal hyperplasia. It can suppress the proliferation and migration of vascular smooth muscle cell (VSMC), stimulate the apoptosis of VSMC and inhibit leukocyte chemotaxis [ 260 ]. NO-releasing coatings have been utilized to prevent restenosis.…”

Section: Perspectives On the Future Surface Modification Strategies Of Zn-based Bmsmentioning

confidence: 99%

A review on current research status of the surface modification of Zn-based biodegradable metals

Yuan

Xia

et al. 2022

Bioactive Materials

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Recently, zinc and its alloys have been proposed as promising candidates for biodegradable metals (BMs), owning to their preferable corrosion behavior and acceptable biocompatibility in cardiovascular, bone and gastrointestinal environments, together with Mg-based and Fe-based BMs. However, there is the desire for surface treatment for Zn-based BMs to better control their biodegradation behavior. Firstly, the implantation of some Zn-based BMs in cardiovascular environment exhibited intimal activation with mild inflammation. Secondly, for orthopedic applications, the biodegradation rates of Zn-based BMs are relatively slow, resulting in a long-term retention after fulfilling their mission. Meanwhile, excessive Zn 2+ release during degradation will cause in vitro cytotoxicity and in vivo delayed osseointegration. In this review, we firstly summarized the current surface modification methods of Zn-based alloys for the industrial applications. Then we comprehensively summarized the recent progress of biomedical bulk Zn-based BMs as well as the corresponding surface modification strategies. Last but not least, the future perspectives towards the design of surface bio-functionalized coatings on Zn-based BMs for orthopedic and cardiovascular applications were also briefly proposed.

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Section: Perspectives On the Future Surface Modification Strategies Of Zn-based Bmsmentioning

confidence: 99%

A review on current research status of the surface modification of Zn-based biodegradable metals

Yuan

Xia

et al. 2022

Bioactive Materials

View full text Add to dashboard Cite

show abstract

Review on Nitric Oxide, Carbon Monoxide and Antisense Based Therapy towards Treatment of Restenosis

Cited by 1 publication

References 56 publications

A review on current research status of the surface modification of Zn-based biodegradable metals

A review on current research status of the surface modification of Zn-based biodegradable metals

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