Review on physicochemical, medicinal and nutraceutical properties of poppy seeds: a potential functional food ingredient

Abstract

The poppy seed plant (Papaver somniferum L.) is well known for its health benefits. It contains plenty of nutrients including proteins, oil content, dietary fiber, antioxidants, tocopherols and other micronutrients. It is also under exploration considering its in vitro bioactive potential against various health issues such as hypertension, pain and cancer. Poppy is mainly grown for its opium and oil contents; however, poppy seeds are also widely used for cooking purposes. Poppy seeds contain various essential bioactive compounds including alkaloids, flavonoids, phenolic compounds and polyunsaturated fatty acids that can be effectively used as food ingredients in various applications. Poppyseed oil is considered a good quality oil owing to its rich polyunsaturated fatty acid content. Thus, tremendous potential exists in poppy seeds to be used as functional food ingredients and nutraceutical agents in various formulations. Medicinal and functional uses of poppy seed have been discussed, including some aspects of the utilization of the poppy seeds in the food industry. Further research is required to bring out its ingredient potential in food and health supplements. Keywords: Poppy, seed oil, health attributes, industrial uses, medicinal uses

Interpol Review of Drug Analysis 2019-2022

“…2019 method for determining the traceability of poppy cultivating areas using QuickBird-2 satellite imaging with ERDAS Imagine and eCognition Developer software for image processing and classification [ 445 ]; characterization of poppy seeds using lab-on-a-chip capillary electrophoresis [ 446 ]; UHPLC-MS/MS method to determine the content of porphyroxine and five primary alkaloids (morphine, codeine, thebaine, noscapine, and papaverine) in opium [ 447 ]; determination of morphine content of different preparations of poppy seed tea by HPLC [ 448 ]; HPLC-PDA method for profiling opioid alkaloids in papaver [ 449 ]; purification and product characterization of lipoxygenase from opium poppy cultures (Papaver somniferum L.) [ 450 ]; sensor for opium alkaloids [ 451 ]; stable isotope labeled internal standards for reducing matrix effect in determination of five opium alkaloids by liquid chromatography-quadrupole linear ion trap mass spectrometry (LC-QqQ(LIT)-MS/MS) [ 452 ]; 2020 FIA method to rapidly monitor the morphine content of poppy seeds [ 453 ]; 2021 elliptic Fourier transforms, with other morphometric descriptors to describe and identify Papaver setigerum, Papaver Somniferum and other Papaver taxa in order to track opium poppy domestication [ 454 ]; review of the chemistry and synthesis of five major opium alkaloids [ 455 ]; LC coupled with linear trap quadrupole and high-resolution Orbitrap multistage mass spectrometry to characterize 44 benzylisoquinoline alkaloids, including 22 BIAs in opium poppy latex and roots extracts using collision-induced dissociation (CID), higher-energy collisional dissociation (HCD), and pulsed Q collision-induced dissociation (PQD) MS2 fragmentation [ 456 ]; review of the physiochemical, medicinal and nutraceutical properties of poppy seeds [ 457 ]; dispersive SPE-HPLC method for determination of five opium alkaloids [ 458 ]; investigation the proportions of morphine, thebaine, noscapine, codeine, oripavine and papaverine alkaloids in nine poppy varieties and 36 lines [ 459 ]; 2022 Papaver Somniferum in Kamini [ 460 ]; machine learning to predict missing link enzymes of benzylisoquinoline alkaloid biosynthesis in Papaver Somniferum [ 461 ].…”

Critical Review on Nutritional, Bioactive, and Medicinal Potential of Spices and Herbs and Their Application in Food Fortification and Nanotechnology

“…Tocotrienols and tocopherols have made the poppy seeds valuable for preventing various diseases like cancer, autoimmune, cardiovascular, metabolic, bone, and neurological disorders. Due to the presence of excessive amounts of tocotrienols and α-tocotrienols in the plasma membrane, the poppy seed oil possessed antioxidant activity and it has the potential to retard the lipid oxidation [ 621 ]. Various secondary metabolites such as saponins, tannins, cardiac glycosides, phytosterols, and terpenoids are present in poppy seed.…”

A randomized, controlled trial on the effectiveness of a proprietary marine lipo-peptide formula vs omega-3 on cytokines profile, anxiety, and pain symptoms in patients with fibromyalgia

“…Among a number of natural supplements suggested for their potential use in treating non-FM stress and anxiety disorders [44][45][46], it appears that the present marine lipopeptide supplementation (LD-1227) is able to affect biomarkers of inflammation and stress together with clinical benefit.…”