2022
DOI: 10.52711/2231-5675.2022.00026
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Review on Simultaneous Equation Method (Vierodt’s Method)

Abstract: The article consists of brief review on Simultaneous equation method (Vierodt’s method). This method is applicable for estimation of those drugs whose spectra overlap properly I.e. If a sample contains two absorbing drug each of which absorbing at λmax of the other, it is possible to determine both drugs by technique of simultaneous equation method. This article consists of the list of various combined dosage form and food sample analyzed by Vierodt’s method with its wavelength, linearity range and choice of s… Show more

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Cited by 13 publications
(2 citation statements)
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“…In RP-HPLC, there are two phases: a polar mobile phase and a non-polar stationary phase. The parameters vary during the development process according to the size of the column, the characteristics of the apparatus, and the wavelength at which the asymmetric peaks and mobile phase are present (Yadav et al, 2017;Vyas et al, 2022).…”
Section: Introductionmentioning
confidence: 99%
“…In RP-HPLC, there are two phases: a polar mobile phase and a non-polar stationary phase. The parameters vary during the development process according to the size of the column, the characteristics of the apparatus, and the wavelength at which the asymmetric peaks and mobile phase are present (Yadav et al, 2017;Vyas et al, 2022).…”
Section: Introductionmentioning
confidence: 99%
“…Analytical quality by design (AQbD) and CCD help in regulatory compliance for RP-HPLC method development, stress testing, or stability-indicating methods (3)(4)(5)(6). UV spectrophotometric methods (simultaneous equation method/ Vierodt') and LC-MS are widely acceptable for the simultaneous estimation of pharmaceutical combinations (7)(8)(9). The presence of impurities or degradants critically affects the stability and pharmacological action of pharmaceutical API and drug products (10)(11)(12)(13)(14).…”
Section: Introductionmentioning
confidence: 99%