Reviscometer Evaluation of the Skin Condition after Applying Retinol and Vitamin C Complex in Menopausal Women

Abstract

Background: Topical application of retinol connected with the improvement of various parameters of aging skin is often used in post-and menopausal women. Vitamin A-vitamin C complex treatments may influence skin surface lipids and boost the fibroblasts activity as well as increase their number, thus inducing the improvement of its elasticity. Objective: In the current paper, we demonstrate and evaluate the impact of retinol and vitamin C complex on the face and neck skin elasticity level in a group of women aged 50-69. Method: Reviscometer RVM 600 (Courage & Khazaka, Germany) was used to measure forehead, cheeks and neck skin elasticity in a group of 21 women. Each of the patients was subjected to four treatment sessions that included skin elasticity measurements before each of the three retinol peels at 3-week intervals and one 3-week after the completion of the therapy. Results: Significant increase in the cheeks and neck skin elasticity was observed in the study group. Conclusion: Treatments including retinol with vitamin C-vitamin A complex significantly influence the improvement of skin elasticity, thus reducing the signs of skin aging.

Retinol derivative as bioinitiator in the synthesis of hydroxyl-functionalized polymethacrylates for micellar delivery systems

“…RET improves elasticity of the skin because it stimulates collagen and glycosaminoglycans synthesis. The anti-aging properties are the consequence of the prevented oxidation stress and the delayed/inhibited matrix degradation by blocking the enzymes which decompose collagen [2]. In addition, RET eliminates sun and hormonal skin discolorations by reducing the size of melanocytes and the amount of melamine.…”

“…It also eliminates discoloration caused by tanning and strengthens blood vessels. VitC as a cofactor of proline and lysine hydroxylase, the key enzymes that cross-link and stabilize collagen fibers [14], stimulates the synthesis of collagen as well as demonstrates antioxidant properties [2,15]. Moreover, vitamin A -vitamin C complex causes an increase in skin elasticity and reduces the signs of skin aging [2].…”

“…VitC as a cofactor of proline and lysine hydroxylase, the key enzymes that cross-link and stabilize collagen fibers [14], stimulates the synthesis of collagen as well as demonstrates antioxidant properties [2,15]. Moreover, vitamin A -vitamin C complex causes an increase in skin elasticity and reduces the signs of skin aging [2]. The low toxic ferulic acid (FA, 4-hydroxy-3-methoxycinnamic acid), which can be absorbed to be easily metabolized in the human body, is another ingredient in cosmetics [16].…”