Revision adenoidectomy—A retrospective study

Monroy, Angelo; Behar, Philomena; Brodsky, Linda

doi:10.1016/j.ijporl.2008.01.008

Cited by 72 publications

(73 citation statements)

References 17 publications

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“…Previous attempts at identifying the pathophysiologic mechanisms have focused on microbiological and immunologic changes in enlarged tonsils and adenoids [4]. Enlargement of the adenoids during early and middle childhood may occur in response to a variety of antigenic challenges including viruses, bacteria, allergens, foods, and environmental irritants [3]. The exposure of the upper aerodigestive tract to gastric secretions results in numerous pathologic conditions such as chronic rhinosinusitis, recurrent otitis media, chronic cough, and airway abnormalities etc.…”

Section: Discussionmentioning

confidence: 99%

“…[9,10]. GER has recently been a popular cause of chronic adenotonsillar hypertrophy in the literature [2][3][4][5]. Reflux into the nasopharynx is unusual in most patients [9] and little is known about the possible role of GER in nasopharyngeal disease [11].…”

Section: Discussionmentioning

confidence: 99%

“…Studies have shown that extraesophageal reflux can cause considerable damage to the less resistant respiratory epithelium of the larynx, trachea, nose, and middle ear [3]. A certain amount of GER is considered normal in infant, but beyond 12 months of age the amount of physiologic reflux approximates that of adults [12].…”

Section: Discussionmentioning

confidence: 99%

“…By the age of 12 months and thereafter, only 8% of children were thought to have GER. In a study conducted by Monroy et al [3], among 72 revision adenoidectomy patients, GER was investigated in 29 patients and 28 of these patients showed GER. Keles et al [2] were investigated frequency of pharyngeal reflux in children with adenoid hyperplasia.…”

Section: Discussionmentioning

confidence: 99%

“…The etiology of chronic adenotonsillar hypertrophy is still unclear. Gastroesophageal reflux (GER) or extraesophageal reflux in children are one of the increasingly recognized and defined causes of adenotonsillar hypertrophy in the literature [2][3][4][5]. If GER is shown to play a significant contributory role in the etiology of adenoid hypertrophy, medical treatment of GER might obviate the need for adenoid surgery.…”

Section: Introductıonmentioning

confidence: 99%

See 4 more Smart Citations

Does Helicobacter Pylori Have a Role in the Etiology of Adenoid Hypertrophy?

Aydın

Aydoğan

Taştan

et al. 2011

Indian J Otolaryngol Head Neck Surg

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To investigate whether there is any association between nasopharyngeal reflux and adenoid hypertrophy in children by using 24-h pH monitoring with dual probe and to determine whether Helicobacter pylori simply colonises in adenoid tissue or it is present there temporarily due to extraesophageal reflux. A prospective study at a tertiary referral center. Thirty-two patients who underwent adenoidectomy, aged ranged between 4 and 13 were included. All children with adenoid hypertrophy underwent 24-h pH monitoring with a dual probe. Proximal probe was placed in the nasopharynx. The presence of nasopharyngeal reflux and gastroesophageal reflux were investigated by 24-h pH monitoring. The presence of H. pylori was investigated in adenoidectomy samples by HP-fast test. Of the 32 patients who underwent adenoidectomy, 5 had nasopharyngeal reflux positivity while 27 patients did not show nasopharyngeal reflux positivity with pH monitorisation. Helicobacter pylori could not be detected in 5 nasopharyngeal reflux positive children while 3 of 27 nasopharyngeal reflux negative children showed H. pylori positivity, one of them in the mucosa and others in the core. This study demonstrated the high incidence of nasopharyngeal reflux and gastroesophageal reflux in adenoid hypertrophy and the possible colonisation of H. pylori in the adenoid tissue. This may change the assesment of children with adenotonsillar hypertrophy in near future. However, more placebo controlled and double blind studies and larger series are still needed to support this hypothesis.

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Section: Discussionmentioning

confidence: 99%