The first resonance peak, Gs1, represents the amplification ratio of seismic motion when resonance between input motion and the local site occurs. The Gs1 is important for understanding amplification characteristics of local site, thus it has been adopted for evaluating site effects in the Japanese Seismic Code. Herein, a simple method for estimating the Gs1 of layered soil profiles is proposed. By replacing a multi-layer soil profile on bedrock with an equivalent one-layer soil profile, the Gs1 and fundamental period are easily obtained. To realize the one-layer profile, we develop a procedure to replace a two-layer soil profile on bedrock with an equivalent single-layer profile. This procedure is then applied successively to a multi-layer soil profile to obtain an equivalent single-layer soil profile. The validity of the proposed method is demonstrated by evaluating 67 representative sites. The results obtained using the proposed procedure agree well with those produced by the wave propagation method.