Revisiting Bacterial Urinary Tract Infection

Bartges, Joseph W.

doi:10.1016/b0-72-160423-4/50051-2

Cited by 13 publications

(20 citation statements)

References 16 publications

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“…Quantitative urinary cultures are used to definitively identify the genus and species of bacteria and sensitivity to antibiotics. [1][2][3][4][5][6][7][8][9] However, owing to the expense, time requirements, and more restricted availability of quantitative urinary culture, veterinarians may rely upon light microscopic examination of urinary sediment for screening patients to (1) tentatively diagnose bacterial UTI, (2) assess the need for urinary culture, or (3) initiate empirical antibiotic therapy based on morphology of the bacteria in uncomplicated cases or those with pending culture results. 8 In our experience, urinary sediment examination and quantitative culture frequently yield discordant results, 10 especially in cats.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of modified Wright‐staining of dried urinary sediment as a method for accurate detection of bacteriuria in cats

Swenson¹,

Boisvert²,

Gibbons-Burgener

et al. 2011

Veterinary Clinical Pathol

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Section: Introductionmentioning

confidence: 99%

Evaluation of modified Wright‐staining of dried urinary sediment as a method for accurate detection of bacteriuria in cats

Swenson¹,

Boisvert²,

Gibbons-Burgener

et al. 2011

Veterinary Clinical Pathol

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“…2 A variety of physical and mucosal defence mechanisms in the feline urinary tract, including highly concentrated urine, present a relatively hostile environment for bacterial growth. 3,4 Studies consistently have shown that bacterial cystitis affects less than 3% of cats presenting with lower urinary signs.…”

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confidence: 99%

Clinical Efficacy and Palatability of Pradofloxacin 2.5% Oral Suspension for the Treatment of Bacterial Lower Urinary Tract Infections in Cats

Litster

Moss

Honnery

et al. 2007

Veterinary Internal Medicne

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Background: Pradofloxacin is a 3rd generation veterinary fluoroquinolone designed to restrict the emergence of antimicrobial resistance during therapy.Hypothesis: Pradofloxacin 2.5% oral suspension is a safe, efficacious, and palatable treatment for bacterial urinary tract infections (UTI) in cats.Animals: Seventy-eight cats presented with lower urinary tract signs and were positive on bacterial culture of urine. Methods: Cats were allocated into 3 treatment groups depending on bacterial susceptibility results: pradofloxacin (n 5 27), doxycycline (n 5 23), or amoxicillin-clavulanic acid (n 5 28). All antimicrobials were presented in palatable liquid form. Posttreatment urine specimens were collected after completion of the course of treatment and submitted for bacterial culture and sensitivity. Owners were questioned before and after treatment about their experiences with administering oral medication to their cats.Results: Posttreatment urine culture was negative in all cats in the pradofloxacin group, but there were 3 treatment failures in each of the other groups. Owners' perceptions of the difficulty of administering oral medication to their cats was more positive posttreatment than pretreatment (P 5 .001; P , .001). There was no difference in palatability among the treatment groups (P . .05).Conclusions and clinical importance: We conclude that pradofloxacin 2.5% oral suspension is a highly effective and safe antimicrobial treatment for bacterial lower urinary tract infection in cats, and that the palatable formulation optimizes owner compliance. These findings make pradofloxacin a useful addition to the veterinary formulary.

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“…A single bacterial pathogen is isolated from approximately 75% infections; 20% of UTIs are caused by 2 coinfecting species, and approximately 5% are caused by 3 species. [3][4][5] The bacteria that most commonly cause UTIs are similar in dogs and cats ( Fig. 1).…”

Section: Bacterial Isolatesmentioning

confidence: 99%

Urinary Tract Infections

Bartges

Olin

2015

Veterinary Clinics of North America: Small Animal Practice

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Urinary tract infection (UTI) occurs when there is compromise of host defense mechanisms and a virulent microbe adheres, multiplies, and persists in a portion of the urinary tract. Most commonly, UTI is caused by bacteria, but fungi and viruses are possible. Urine culture and sensitivity are the gold standards for diagnosis of bacterial UTI. Identifying the location of infection (eg, bladder, kidney, prostate) as well as comorbidities (eg, diabetes mellitus, immunosuppression) is essential to guide the diagnostic and therapeutic plan. Antimicrobial agents are the mainstay of therapy for bacterial UTI and selected ideally based on culture and sensitivity.

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Revisiting Bacterial Urinary Tract Infection

Cited by 13 publications

References 16 publications

Evaluation of modified Wright‐staining of dried urinary sediment as a method for accurate detection of bacteriuria in cats

Evaluation of modified Wright‐staining of dried urinary sediment as a method for accurate detection of bacteriuria in cats

Clinical Efficacy and Palatability of Pradofloxacin 2.5% Oral Suspension for the Treatment of Bacterial Lower Urinary Tract Infections in Cats

Urinary Tract Infections

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