Revisiting flow‐chemiluminescence techniques: pharmaceutical analysis

Abstract

The state of the art in flow-chemiluminescence (flow-CL) technique for automated pharmaceutical analysis is reviewed. Flow-CL approaches have become powerful and promising tools for pharmaceutical screening in recent years due to their simplicity, low cost and high sensitivity. Because of these advantages, these methods have been widely used for pharmaceutical analysis in recent years. The literature reviewed covers papers of analytical interest that appeared between 2007 and mid-2012 and have been divided into several sections based on fundamental types of CL systems employed. Furthermore, entries have been summarized alphabetically in tabular form giving details of analytical figures of merit of the methods.

Advances in nanomaterial-assisted cataluminescence and its sensing applications

“…While liquid-phase CL has shown great potential application in food analysis [10,11], pharmaceutical analysis [12], immunoassay [4,6,8], DNA analysis [4,8], and other biological analyses [7,13,14], gas-phase CL plays an important role in measuring and monitoring gaseous or volatile components in the atmospheric environment [15][16][17][18][19]. Since 1970, various CL methods for atmospheric NO analysis have been established and some recommended for environmental air monitoring.…”

Flow Injection-Chemiluminescence Method for Determination of Hyoscine Butylbromide Using Silver(III) as Oxidizing Agent

“…[27][28][29] Silver(III), copper(III) and nickel(IV) have been used as oxidizing agents in the CL reactions using polydentate ligands. 30 Transition metals at unstable high oxidation states including diperiodatoargentate(III) (DPA)/silver(III)/complex, [Ag (HIO6)2] 5-, is considered to be a strong oxidizing agent with the reduction potential of 1.74 V in alkaline medium.…”

Determination of naphazoline hydrochloride in biological and pharmaceutical samples by a quantum dot‐assisted chemiluminescence system using response‐surface methodology

“…In a period of no more than two decades, chemiluminescence (CL)-based analytical techniques, which were once being mentioned as "rather unknown" (1), have evolved into well-known techniques, providing a research field that is experiencing successive expansion and progression in terms of both instrumental aspects and the chemistry involved (2)(3)(4)(5)(6)(7)(8)(9). The attempts to extend the chemical territory of CL are partly focused on discovering new CL reactions and investigation of their applicability to real samples.…”