Revisiting microbial exopolysaccharides: a biocompatible and sustainable polymeric material for multifaceted biomedical applications

Kiran, Neelakanta Sarvashiva; Yashaswini, Chandrashekar; Singh, Sudarshan; Prajapati, Bhupendra Gopalbhai

doi:10.1007/s13205-024-03946-3

3 Biotech

2024

DOI: 10.1007/s13205-024-03946-3

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Revisiting microbial exopolysaccharides: a biocompatible and sustainable polymeric material for multifaceted biomedical applications

Neelakanta Sarvashiva Kiran,

Chandrashekar Yashaswini,

Sudarshan Singh

et al.

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Unveiling the potential of chitosan-coated lipid nanoparticles in drug delivery for management of critical illness: a review

Das,

Kapoor,

Singh

et al. 2024

Zeitschrift Für Naturforschung C

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Chitosan (CT), a natural, cationic, chemically stable molecule, biocompatible, biodegradable, nontoxic, polysaccharide derived from the deacetylation of chitin, has very uniquely surfaced as a material of promise for drug delivery and biomedical applications. For the oral, ocular, cutaneous, pulmonary, and nose-to-brain routes, CT-coated nanoparticles (CTCNPs) have numerous advantages, consisting of improved controlled drug release, physicochemical stability, improved cell and tissue interactions, and increased bioavailability and efficacy of the active ingredient. CTCNPs have a broad range of therapeutic properties including anticancer, antiviral, antifungal, anti-inflammatory, antibacterial properties, treating neurological disorders, and other diseases. This has led to substantial research into the many potential uses of CT as a drug delivery vehicle. CT has also been employed in a wide range of biomedical processes, including bone and cartilage tissue regeneration, ocular tissue regeneration, periodontal tissue regeneration, heart tissue regeneration, and wound healing. Additionally, CT has been used in cosmeceutical, bioimaging, immunization, and gene transfer applications. CT exhibits a number of biological activities, which are the basis for its remarkable potential for use as a drug delivery vehicle, and these activities are covered in detail in this article. The alterations applied to CT to obtain the necessary properties have been described.

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Unveiling the potential of chitosan-coated lipid nanoparticles in drug delivery for management of critical illness: a review

Das,

Kapoor,

Singh

et al. 2024

Zeitschrift Für Naturforschung C

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show abstract

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Revisiting microbial exopolysaccharides: a biocompatible and sustainable polymeric material for multifaceted biomedical applications

Cited by 1 publication

References 149 publications

Unveiling the potential of chitosan-coated lipid nanoparticles in drug delivery for management of critical illness: a review

Unveiling the potential of chitosan-coated lipid nanoparticles in drug delivery for management of critical illness: a review

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