Rezum Outcomes in Relationship to Number of Injections: Is Less More?

Babar, Mustufa; Loloi, Justin; Azhar, Umair; Tang, Kevin; Ines, Matthew; Singh, Sandeep; Iqbal, Nazifa; Ciatto, Michael

doi:10.1089/end.2022.0390

Cited by 9 publications

(10 citation statements)

References 20 publications

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“…This study adds to the published literature assessing Rezum outcomes with respect to the number of injections used during treatment. We previously have shown that at the 1‐year follow‐up, using more injections did not improve LUTS to a greater degree but instead increased the odds of adverse events, including gross haematuria, penile burning, penile pain, and dysuria [3]. The present study suggests that at the 4‐year follow‐up, there was no relationship between the number of injections and improvement in LUTS.…”

Section: Outcome Measure All Patients Number Of Injections P One Two ...mentioning

confidence: 96%

“…Recently, Aladesuru et al. [2] and our group [3] have suggested a ‘less is more’ treatment approach regarding the number of injections utilised during treatment, as using fewer injections was shown to be a safer treatment strategy without significantly compromising Rezum's efficacy in improving LUTS. However, these two studies only assessed outcomes up to 1 year.…”

Section: Outcome Measure All Patients Number Of Injections P One Two ...mentioning

confidence: 99%

“…A single‐office retrospective study was conducted on patients from a multi‐ethnic population treated with Rezum by two urologists between 1 December 2017 and 30 April 2019. Inclusion criteria and perioperative protocols have been previously described [3]. Men were stratified into one of four cohorts based on the number of injections received per lateral prostatic lobe: one, two, three, or four injections.…”

Section: Outcome Measure All Patients Number Of Injections P One Two ...mentioning

confidence: 99%

“…The Rezum System (Rezum; Boston Scientific, Marlborough, MA, USA) is a relatively novel minimally invasive surgical therapy that uses a retractable needle to inject water vapour at 103 °C into obstructive prostatic lobes to treat LUTS secondary to BPH [1]. Recently, Aladesuru et al [2] and our group [3] have suggested a 'less is more' treatment approach regarding the number of injections utilised during treatment, as using fewer injections was shown to be a safer treatment strategy without significantly compromising Rezum's efficacy in improving LUTS. However, these two studies only assessed outcomes up to 1 year.…”

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confidence: 98%

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Water vapour thermal therapy (Rezum) outcomes at 4 years in relationship to the number of injections: is the ‘less is more’ treatment approach durable?

et al. 2023

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Section: Outcome Measure All Patients Number Of Injections P One Two ...mentioning

confidence: 96%

Section: Outcome Measure All Patients Number Of Injections P One Two ...mentioning

confidence: 99%

Section: Outcome Measure All Patients Number Of Injections P One Two ...mentioning

confidence: 99%

mentioning

confidence: 98%

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Water vapour thermal therapy (Rezum) outcomes at 4 years in relationship to the number of injections: is the ‘less is more’ treatment approach durable?

et al. 2023

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“…1). Overtreatment will likely increase the risk of early postoperative complications including haematuria, UTI, penile discomfort, and dysuria [4]. This can in turn prolong the time taken for the withdrawal of urological medication.…”

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confidence: 99%

Is less indeed more for Rezum water vapour treatment of the lateral prostate lobes?

Hindley

2023

BJU International

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Feasibility assessment of catheter-free water vapor thermal therapy for treatment of benign prostatic hyperplasia

Nguyen,

Winograd,

Codelia-Anjum

et al. 2024

World J Urol

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Purpose To investigate safety and feasibility of performing water vapor thermal therapy (WVTT; Rezum, Boston Scientific, Marlborough, MA, USA) without postoperative catheterization among men with benign prostatic hyperplasia. Methods This is a prospective, single arm, unblinded pilot study of 20 consecutive male patients ages 40–80 who underwent WVTT at a single academic institution. All patients underwent 1 injection per lobe at the point of maximal obstruction based on visualization. Primary outcome was evaluation of voiding parameters, symptom scores, and need for catheterization at 3 day, 1, 3, and 6 month follow up compared to baseline visit 30 days prior to surgery. Results Mean age was 65 years (range 55–75). Mean prostate volume and PVR were 43 cc (range 30–68) and 89 cc, with 30% (n = 6) having median lobes. Patients received 2–3 treatments based on presence of bilobar versus trilobar hyperplasia. One patient (55 cc prostate, no median lobe) required catheterization for acute urinary retention on postoperative day 2. No patients required antibiotics for urinary tract infection or inpatient readmission within 30 days. Qmax significantly increased from 6 mL/s to 8, 13, 12, and 14 at 3 days, 1, 3, and 6 months (p < 0.05). IPSS decreased from 17 preoperatively to 10, 6, 7, and 8 (p < 0.05). No significant differences were noted in PVR, IIEF, MSHQ-EjD, or SF-12. Conclusions In well-selected men, catheter-free WVTT is feasible and improved voiding parameters and symptom scores. No changes in sexual function, infectious complications, or readmission were noted. Only 1 patient (5%) required postoperative catheterization within 30 days.

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Rezum Outcomes in Relationship to Number of Injections: Is Less More?

Cited by 9 publications

References 20 publications

Water vapour thermal therapy (Rezum) outcomes at 4 years in relationship to the number of injections: is the ‘less is more’ treatment approach durable?

Water vapour thermal therapy (Rezum) outcomes at 4 years in relationship to the number of injections: is the ‘less is more’ treatment approach durable?

Is less indeed more for Rezum water vapour treatment of the lateral prostate lobes?

Feasibility assessment of catheter-free water vapor thermal therapy for treatment of benign prostatic hyperplasia

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