RF - Generalized Morphea: Definition and Associations

García‐Vázquez, Alejandro; Guillén-Climent, Santiago; Quiles, María Dolores Ramón

doi:10.1016/j.adengl.2019.05.023

Cited by 1 publication

(1 citation statement)

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“…This type of morphea is differentiated from scleroderma by the absence of Raynaud's, sclerodactyly, no facial involvement, no nail fold involvement in capillaroscopy, no visceral involvement, and no specific autoantibodies. Although systemic sclerosis has been reported as a paraneoplastic phenomenon, the association of morphea with cancer has not been demonstrated ( 11 ).…”

Section: Discussionmentioning

confidence: 99%

Pansclerotic Morphea Following COVID-19: A Case Report and Review of Literature on Rheumatologic and Non-rheumatologic Dermatologic Immune-Mediated Disorders Induced by SARS-CoV-2

et al. 2021

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While mucocutaneous manifestations of COVID-19 have been frequently reported and added to our knowledge every day during the pandemic, another issue is the COVID-related diseases that can present as intensified lesions of underlying diseases, a new disease, or changes in the behavior of an old lesion. Given that immune system overreaction and cytokine storm are among the most prominent events in COVID-19, the incidence of autoimmune diseases is expected to increase after COVID-19, as confirmed in several reports. To increase the body of knowledge about short- and long-term outcomes of COVID-19 for specialists, it is essential that similar cases be reported and collected for years to come. The present study investigated a case of pansclerotic morphea that rapidly progressed a few weeks after infection with COVID-19 in a 57-year-old woman with no history of any autoimmune skin or rheumatic diseases. She was prescribed outpatient COVID-19 treatment of azithromycin, vitamins D and C, and then quarantined for 2 weeks. The manifestations of the disease were exacerbated at each follow-up and sampling visit at short intervals. This kind of pansclerotic morphea is reported for the first time.

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Section: Discussionmentioning

confidence: 99%