2018
DOI: 10.2459/01.jcm.0000550071.87910.91
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Rf06 the Choice of the Best Prosthetic Valve in Cardiac Ochronosis

Abstract: Background: Alkaptonuria is a rare autosomal genetic anomaly of the metabolism of tyrosine, and is characterized by the accumulation of homogentisic acid in the extracellular matrix with destruction of numerous tissues. Ocronosis is rarely associated with abnormalities of the cardiovascular system. The most common clinical manifestation is aortic valve stenosis. There is no specific therapy for alkaptonuria, limiting itself to the treatment of only the complications of the pathology. … Show more

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