This work is conducted to deal with the information security of enterprise management under the background of current global informatization, popularize the modern Internet of Things (IoT) management technology of enterprises, and maintain the information security of enterprises and provide modern upgrading means for enterprise management. In this work, it firstly introduces the application scenarios of current Internet and Artificial Intelligence (AI) technology and expounds the IoT technology. Secondly, the enterprise management platform is designed, the requirements of enterprise modern management are analyzed, and then the design requirements of system functions and the design of the information security architecture of the IoT are proposed. Furthermore, an enterprise information security management platform is designed, which covers four parts: IoT data mining management, equipment management, key management, and database management. In addition, the performance of the security management platform is tested from four parts: concurrency testing, stress testing, large data volume testing, and security testing. The research results show that the IoT-based enterprise information security management platform designed in this work under the background of AI has perfect functions and stable performance of each module. Concurrency testing, stress testing, large data volume testing, and stability testing are performed on it, and the success rate of the platform in each task reaches 100%. The average response time of concurrent testing and stress testing is about 0.13 seconds, and that of the event entry events is 0.25 seconds. The central processing unit (CPU) occupancy rate in each monitoring task is always lower than 20%. Therefore, it is determined that the performance of the IoT-based enterprise information security management platform designed in this work is sufficient to meet the daily management of enterprises. This work can provide a guarantee for enterprise information security management using AI technology, setting an example for future related research.