Rh(III)-Catalyzed Oxidative Domino C–H/N–H Annulation: Diarylureas as Arylamine Donors for the Assembly of Indolo[2,1-a]isoquinolines

Abstract

An efficient and convenient Rh(III)-catalyzed double aryl C(sp2)−H bond and N−H activation and annulation reaction is reported for the synthesis of indolo[2,1-a]isoquinolines in the presence of the Cu(OAc) 2 oxidant under heating conditions. Distinct from previous works with other arylamine donors, one molecule of 1,3-diarylurea can serve as a precursor of two molecules of arylamine in the reaction with diaryl-substituted alkynes.

A magnetic Fe@PANI catalyst for the selective oxidation of sulphide under mild and green conditions

“…Since the reaction could be restrained by 2,2,6,6-tetramethylpiperidoxyl (TEMPO), it is supposed to be a free radical reaction (Table 1, entry 8). 17 Salicylic acid trapping experiment further confirmed that the hydroxyl radical was involved in the process (Fig. S1 in ESI†).…”

Photocatalytic aerobic oxidative deoximation reaction with degradable rhodamine B

“…Thus, it could be concluded that the photocatalytic process might occur through a free radical reaction mechanism. 18…”