Rh(i)-Catalyzed [3+2] annulation reactions of cyclopropenones with amides

Abstract

Rh(i)-Catalyzed [3+2] annulation reactions of cyclopropenones with amides are reported.

Rh(III)-Catalyzed [3 + 3] Annulation Reaction of Cyclopropenones and Sulfoxonium Ylides toward Trisubstituted 2-Pyrones

“…On the basis of literature reports − , and from the observations of the experiment results, a plausible catalytic cycle for this annulation is proposed in Scheme . First, cyclometallation between substrate 1 and Rh complex occurs, delivering a 4-membered rhodacyclic intermediate A . Intermediate A is converted into intermediate C through two possible pathways.…”

Palladium-Catalyzed C–C Bond Activation of Cyclopropenone: Modular Access to Trisubstituted α,β-Unsaturated Esters and Amides

“…Recently, through the β-carbon elimination pathway, we have demonstrated C–C bond activation of cyclopropanol to achieve 1,6-diketone derivatives . In this vein, the smallest Huckel aromatic system cyclopropenone is less investigated . Although, Rh-, Pt-, and Ni-catalyzed ring opening of cyclopropenone was reported before, limited scope and lack of mechanistic evidence offers a multitude of scopes to explore the C–C bond activation of cyclopropenone.…”

Enantioselective palladium-catalyzed C(sp2)–C(sp2) σ bond activation of cyclopropenones by merging desymmetrization and (3 + 2) spiroannulation with cyclic 1,3-diketones

“…41 In particular, the transition-metal-catalyzed transformations of cyclopropenones involving the carbon-carbon bond activation have been an active research area in the past years. Among various synthetic approaches based on the chemical reactivity of the cyclopropenones, [42][43][44][45][46][47][48][49][50][51][52][53][54][55][56][57][58][59] enantioselective version of transition-metal-catalyzed carboncarbon bond activation and subsequent ring opening or ring expansion reactions of cyclopropenones remain underexplored.…”