Rhabdomyolysis and Acute Kidney Injury Associated with Salmonella Infection: A Report of 2 Cases

Lee, In Hee; Ahn, Dong Jik

doi:10.12659/ajcr.936407

Cited by 1 publication

(3 citation statements)

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“…Elevated serum creatine kinase (CK) could indicate muscle cell damage due to muscle trauma, strenuous exercise, or the use of certain drugs 1–3 . Numerous cytoplasmic components within muscle cells exit through the damaged sarcolemma, including myoglobin and electrolytes, which are involved in acute kidney injury (AKI) and possible cardiac dysrhythmia 1,4,5 …”

Section: Introductionmentioning

confidence: 99%

“… 1 , 2 , 3 Numerous cytoplasmic components within muscle cells exit through the damaged sarcolemma, including myoglobin and electrolytes, which are involved in acute kidney injury (AKI) and possible cardiac dysrhythmia. 1 , 4 , 5 …”

Section: Introductionmentioning

confidence: 99%

“…[1][2][3] Numerous cytoplasmic components within muscle cells exit through the damaged sarcolemma, including myoglobin and electrolytes, which are involved in acute kidney injury (AKI) and possible cardiac dysrhythmia. 1,4,5 Motor signs associated with seizures, including tonic, clonic, and myoclonic movements, can be considered muscle overuse. 1,6 Seizures can induce elevated CK levels, which might serve as a marker to distinguish epileptic seizures from nonepileptic seizures.…”

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confidence: 99%

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Characteristics and treatments of patients with significantly elevated creatine kinase levels induced by seizures: Case report and literature review

Wang,

Yang,

et al. 2023

Clinical Case Reports

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Key Clinical MessageMotor signs accompanying seizures have been considered to result in overexertion of muscles and have the ability to cause elevated levels of serum creatine kinase (CK). There were no previous studies on the treatment of seizure‐induced elevated CK. We summarized the characteristics and treatments of six patients with significant elevation of CK after seizure onset. There were four males and two females, the age range was 16–68 years. The CK levels were greater than 5000 U/L in five of the six patients and the highest CK level was 39,300 U/L. All patients exhibited an estimated glomerular filtration rate (eGFR) < 90 mL/min/1.73m2. No patient developed renal failure or required continuous renal replacement therapy. We determined that serial assessment of CK, myoglobin, eGFR, and electrolytes should be performed in patients following seizures. Furthermore, fluid resuscitation, urine alkalization, and diuretic agents should be administrated when CK are significantly elevated after seizure onset. Serial assessment of CK levels after seizures should be performed, especially when the patient experiences electrolyte disorders. Fluid resuscitation, urine alkalization, and diuretic agents also should be administrated to patients when they exhibit a significantly elevated CK or myoglobin after seizures.

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Section: Introductionmentioning

confidence: 99%