Rhabdomyolysis And Delirium Tremens In An Alcoholic Patient: Case Report / Rabdomiólise E Delirium Tremens Em Paciente Alcóolatra: Relato De Caso

Lacerda, Diego Rodrigues Naves Barbosa; Argondizzi, Gabriela Teixeira; Machado, Mariana Vilela; Rodrigues, Karine Mendonça Davi; Silva, Clarissa Bernardes de Oliveira; Nunes, Paulo Vinicius Rabelo; Rosa, Augusto Geraldo

doi:10.34117/bjdv7n6-374

Cited by 1 publication

(1 citation statement)

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“…Regarding alcohol consumption, its pathophysiology in the disease can be explained by the fact that ethanol inhibits calcium accumulation in the sarcoplasmic reticulum of muscles, affects the cell membranes of the muscles, and inhibits the sodium-potassium pump that maintains cell integrity [55].…”

Section: Medications Toxins and Illicit Drugsmentioning

confidence: 99%

Acute Kidney Injury Due to Rhabdomyolysis: A Review of Pathophysiology, Causes, and Cases Reported in the Literature, 2011–2021

Da Silva Junior,

Neves Pinto,

Campelo Fraga

et al. 2023

Rev. Colomb. Nefrol.

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Introduction: Rhabdomyolysis (RML) is characterized by the destruction of muscle fibers and the release of intracellular constituents, with the potential to cause local and systemic complications, such as acute kidney injury (AKI). Methodology: Literature review in which articles were analyzed between 2011 and 2021, from the PubMed database. Results: RML can occur directly, indirectly, or secondary to trauma, metabolic disorders, medications and exogenous intoxication. Clinically, it may present asymptomatically, but a classic triad consisting of myalgia, generalized weakness and dark urine is common. AKI, despite being a late complication, is common. Laboratory markers used to diagnose RML are serum Creatine Kinase (CK) and serum and urinary Myoglobin, with CK being more sensitive. The approach can occur through classic strategies, such as hydration, diuretics, alkalinization and renal replacement therapy (RRT), but also through new strategies, such as iron chelators and antioxidants; anti-inflammatories and new extracorporeal blood filter. Discussion: Trauma was the most common etiology of AKI due to RML, with a minority of patients requiring RRT. Furthermore, it was found that COVID-19 infection did not result in major kidney complications. Strenuous exercise has been shown to be a rare etiology of AKI due to RML. Other less common causes were drug use/intoxication and metabolic diseases, the majority of which patients did not require RRT or had a favorable outcome. Conclusion: RML is a potentially serious condition, making it important to know its causes and management in order to reduce the chances of serious complications and to avoid patient death.

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Section: Medications Toxins and Illicit Drugsmentioning

confidence: 99%