Rhabdomyolysis-induced acute kidney injury requiring hemodialysis in a patient on long-term, moderate-intensity rosuvastatin: a case report and literature review

Abstract

Statins are widely used to prevent cardiovascular diseases. However, rhabdomyolysis is a wellknown adverse effect of statin use. The present report highlights a case of rhabdomyolysis-induced acute kidney injury (AKI) in a patient receiving long-term moderate-intensity rosuvastatin. Muscle weakness occurred 3 years after rosuvastatin administration. Myopathy and acute kidney injury resolved completely after withdrawal. To our knowledge, there have been no previously reported cases of moderate-intensity rosuvastatin-induced rhabdomyolysis-induced severe AKI requiring renal replacement therapy. This case report shows that moderate-intensity rosuvastatin therapy is also associated with risk of severe rhabdomyolysis.