2011
DOI: 10.1136/bcr.12.2009.2552
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Rhabdomyolysis with simvastatin

Abstract: As 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors ('statins') are being increasingly prescribed for the prevention of cardiovascular disease, this case report describes adverse effects of statin therapy which can sometimes be fatal. It highlights the need for physicians to be aware of individual patient risk factors predisposing to statin induced myopathy. It also highlights the need for further research into cholesterol lowering drugs which do not have such side effects. When prescribing… Show more

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Cited by 3 publications
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“…The prognosis is usually excellent if the underlying mechanism of rhabdomyolysis can be identified and reversed, whenever it is possible. After 3-30 days of withdrawal of statins the muscular symptoms usually decrease, and the CPK normalizes [8]. …”
Section: Discussionmentioning
confidence: 99%
“…The prognosis is usually excellent if the underlying mechanism of rhabdomyolysis can be identified and reversed, whenever it is possible. After 3-30 days of withdrawal of statins the muscular symptoms usually decrease, and the CPK normalizes [8]. …”
Section: Discussionmentioning
confidence: 99%