Rhabdomyoma in the base of the tongue : A case report

Salameh, Bairak; Ghareeb, Ayham; Badran, Hadeel; Salameh, Hayan; Hajali, Wahib; Alassaf, Areej

doi:10.1016/j.ijscr.2022.107239

Cited by 3 publications

(1 citation statement)

References 6 publications

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“…A-RMs are considered rare in the oral cavity and there are about 80 cases reported in the Englishlanguage literature [5] . The etiology of its pathogenesis is unclear and it may originate from the third or fourth branchial arch; it may also be related to genetic alterations in striated muscle development, as balanced translocations of chromosome pairs 15 and 17 have been identi ed in some patients; it has also been suggested that it may be associated with chronic irritation [6][7][8][9] .…”

Section: Discussionmentioning

confidence: 99%

Clinicopathologic study of the adult rhabdomyoma in the oral and maxillofacial region

Zhang,

Huang,

et al. 2024

Preprint

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Objectives This study aimed to explore the clinicopathological characteristics of adult rhabdomyoma (A-RM) in the oral and maxillofacial region. Materials and Methods We analyzed seven cases of A-RM in the oral and maxillofacial region, focusing on the clinical manifestations, imaging findings, histopathological features, differential diagnosis, treatment, prognosis, and relevant literature review. Results The age range of the seven A-RM cases was 4 to 83 years old. Six cases were male and one case was female. Three cases occurred on the floor of the mouth and one case on the tongue. All A-RM cases presented as slow-growing, painless masses. The lesions were lobulated, red-brown nodules with well-defined margins. Histologically, they consisted of densely packed, large, round and polygonal cells with abundant granular eosinophilic cytoplasm. Cross-striations and vacuoles were observed in the cytoplasm. Tumor cells were positive for desmin, myoglobin and myogenin, and some tumor cells were positive for SMA, MyoD1 and S-100 protein. PAS staining was also positive among tumor cells and could be digested by diastase. Conclusion Histological examination is the main diagnostic criterion for A-RM. The detection of cross-striations and immunohistochemical expression of myogenic proteins in the cytoplasm are crucial for accurate diagnosis. Radical resection is the main treatment modality with generally favorable prognosis.

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Section: Discussionmentioning

confidence: 99%

Clinicopathologic study of the adult rhabdomyoma in the oral and maxillofacial region

Zhang,

Huang,

et al. 2024

Preprint

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Rhabdomyoma of the Oral Cavity Mimicking Reactive Lesions: A Case Report and Review of the Literature

Mahdavi,

Saebnoori,

Tabatabaie-Zadeh

2023

Ear Nose Throat J

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Extracardiac rhabdomyoma is a tumor that rarely occurs in head and neck region. Adult and fetal types of extracardiac rhabdomyoma are diagnosed only by histopathological examination. In the oral cavity, this lesion usually affects the mouth floor and tongue. Despite the low incidence, adult rhabdomyoma should be considered in the differential diagnosis of oral cavity lesions, and histopathological evaluation might be helpful for the final diagnosis. This study aims to report a rare case of rhabdomyoma mimicking reactive lesions and review the literature. A 34-year-old male was referred to the pathology department with a yellowish sessile lesion in the labial maxillary vestibule. During an excisional biopsy, a mass of unencapsulated soft tissue beneath the vestibular mucosa was observed. The yellowish color in clinical features has led to lipoma as the initial clinical diagnosis. The histological examination exhibited an encapsulated, well-circumscribed benign neoplasm composed of multiple lobules of large polygonal cells with prominent abundant granular eosinophilic cytoplasm. No cellular atypia was observed. Diagnosis of the adult type of rhabdomyoma was made by collective agreement. Rhabdomyoma can be mistaken for other reactive lesions and may resemble their appearance.

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Medical conditions associated with concurrent dysphagia and dysphonia

Myszel,

Henryk Skarzynski

2024

Swallowing - Problems and Management [Working Title]

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Swallowing and voice production are important processes enabling a comfortable life. For appropriate alimentation, effective passage of food and fluids through a digestive system is necessary. Interpersonal communication depends on good voice and speech. Conditions associated with swallowing and speech problems leads dysfunctions and seriously affect the patient’s comfort of living. This chapter is a review of medical conditions associated with concurrence of dysphonia and dysphagia. There are a large number of medical conditions leading to the simultaneous occurrence of swallowing problems and hoarseness. The diversity of disorders is a serious interdisciplinary issue. Diagnostics of concurrent dysphagia and dysphonia is complicated and requires a holistic interdisciplinary approach. The reasons include functional and organic dysfunctions, neurological conditions, tumors, vascular disorders, autoimmune inflammations, post-operative complications, post-COVID complications, and others. Our research was conducted by reviewing PubMed and Scopus network using key words “dysphagia”, “dysphonia”, “hoarseness.” We found 966 publications, then narrowed the search to 99 articles describing medical conditions and case reports, which present with dysphagia and dysphonia occurring together. Detailed analysis enabled us to categorize the disorders into groups, depending on characteristics and body region involved in the pathological process. Finally, the description of the medical conditions was done systematically according to those groups.

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Rhabdomyoma in the base of the tongue : A case report

Cited by 3 publications

References 6 publications

Clinicopathologic study of the adult rhabdomyoma in the oral and maxillofacial region

Clinicopathologic study of the adult rhabdomyoma in the oral and maxillofacial region

Rhabdomyoma of the Oral Cavity Mimicking Reactive Lesions: A Case Report and Review of the Literature

Medical conditions associated with concurrent dysphagia and dysphonia

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