Rhabdomyomatous Mesenchymal Hamartoma Presenting as a Midline Mass on a Chin

Kim, Hyeonwoo; Chung, Jee Hyeok; Sung, Ha Min; Kim, Sukwha

doi:10.7181/acfs.2017.18.4.292

Cited by 13 publications

(21 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Most of the STHs present as a single lesion as seen in our cohort, and only two cases to our knowledge have been reported presenting as multiple lesions one of which was in a 2‐day‐old patient with two striated muscle hamartomas, one on the lower back and the other in the right buttock, 39 and in a 15‐year‐old boy with seven nodules on his left cheek 47 . The mean size of our STHs was 5.7 mm (±3.6), which is in keeping with most of the reported cases which are ≤1 cm, 14,36,37,40,49,52,55,57,63,64 with only one of our cases being >1 cm. However, multiple cases have been reported measuring >1 cm 38,39,41‐43,45‐47,50,51,53,54,58 with the largest case to our knowledge measuring 4.9 × 3.5 × 3 cm 60 …”

Section: Discussionsupporting

confidence: 89%

“…STH most commonly presents in the head and neck as in our cases (11 cases, 91.7%) specifically in the midline chin region 14,37,42,46,57,58,62 . Only one of our cases presented outside of the head and neck region, specifically in the perineum as an inflamed skin tag.…”

Section: Discussionmentioning

confidence: 53%

“…Histopathologically the lesions were characterized by striated muscle proliferation on the dermis. Since then more than 60 cases have been reported in the literature, with a preference for pediatric patients, especially for newborns and infants, arguing for a true congenital nature to this lesion 13,36‐58 . To date, the largest case series described five cases, with three cases presenting in the pediatric age and the remaining two cases presenting in a 48‐ and a 54‐year‐old patients 14 .…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Smooth muscle hamartoma and striated muscle hamartoma: Clinicopathologic characterization of two rare entities and literature review

González

Dehner

2020

J Cutan Pathol

View full text Add to dashboard Cite

Smooth muscle hamartoma (SMH) and striated muscle hamartoma (STH) are anomalous proliferations of smooth muscle or striated muscle, respectively, in anatomic sites where these tissues are normally present. To date, only limited cases have been reported describing these lesions. In this study, we sought to characterize the clinicopathologic features of both SMH and STH. A total of 27 cases of SMH and 12 cases of STH from 1990 to 2020 were identified. SMH cases had a slight male predominance (63%) and a mean age of presentation of 20 years (range: 4 months‐91 years), with a mean size of 9.3 mm (±13.3). In contrast, STH were equally distributed in gender, with a mean age of presentation of 40 years (range: 3 months‐66 years) and a mean size of 5.7 mm (±3.6). SMH were more commonly located in the torso and extremities (70%) and STH in the head and neck area (92%). One case of SMH recurred after 1.1 years and in the initial diagnosis the lesion was present at the tissue edge. None of the cases of STH had a recurrence. We present the largest cohort of SMH and STH, and report the first case of a recurrent SMH, suggesting the importance of obtaining a clean margin for these lesions.

show abstract

Section: Discussionsupporting

confidence: 89%

Section: Discussionmentioning

confidence: 53%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Smooth muscle hamartoma and striated muscle hamartoma: Clinicopathologic characterization of two rare entities and literature review

González

Dehner

2020

J Cutan Pathol

View full text Add to dashboard Cite

show abstract

“…At the caudal end are seromucinous glands in the dermis layer as well as the characteristic upper respiratory type pseudostratified ciliated epithelium at the sinus ending [7]. CMCC is often initially misinterpreted by physicians as a branchial cleft deformity, TGDC, or other congenital malformations [8,9]. Gargan et al [10] reported 12 misdiagnosed midline cervical cleft cases from 612 thyroglossal diseases and branchial cleft sinus diseases in 30 years.…”

Section: Discussionmentioning

confidence: 99%

Congenital midline cervical cleft: An easily misdiagnosed disease

Kang

Kim

2020

Arch Craniofac Surg

View full text Add to dashboard Cite

Congenital midline cervical cleft is a rare congenital disease. The disease is often misdiagnosed as a branchial cleft deformity, thyroglossal duct cyst, or other skin diseases. It has the following characteristics: skin defect at the midline of the anterior neck, a skin tag at the upper end of the lesion, and a blind sinus tract at the caudal aspect with or without mucoid discharge. Treatment is usually for aesthetic purposes; therefore, early surgical en bloc resection with Z-plasty or W-plasty is recommended to reduce recurrence and scar formation.

show abstract

“…Though originally called striated muscle hamartoma, it was subsequently coined RMH by Mills in 1989, and has since also been referred to as congenital midline hamartoma 2 . Since its original description, 67 cases have been reported in the literature 3 . RMH presents most commonly in midline sites of the head and neck region in newborns or young children, and is histopathologically characterized by a haphazard dermal proliferation of striated muscle admixed with adipose tissue and adnexal structures.…”

Section: Introductionmentioning

confidence: 99%

Rhabdomyomatous mesenchymal hamartoma presenting as a chin nodule in a 15‐year‐old male

Marinelli

Wohltmann

Myers³

et al. 2020

J Cutan Pathol

View full text Add to dashboard Cite

Rhabdomyomatous mesenchymal hamartoma (RMH), also known as congenital midline hamartoma and striated muscle hamartoma, is a rare congenital malformation presenting most commonly in midline sites of the head and neck region. Since its first description in 1986, 67 cases have been reported to date. We report a case of RMH presenting as a chin nodule in an otherwise healthy 15‐year‐old male. The patient presented with a dome‐shaped subcutaneous lesion on his chin which had been present since birth, but had grown and was interfering with his ability to shave. He otherwise had no history of congenital anomalies or malformations. Histopathological examination of the excised lesion revealed a haphazard proliferation of striated muscle admixed with adipose tissue and adnexal structures within the dermis and subcutaneous tissue, consistent with a diagnosis of RMH. While the majority of reported cases are of newborns or children under 3 years of age, RMH may not come to clinical attention until later in life. This rare malformation should be included in the differential diagnosis of lesions containing dermal striated muscle and/or adipose tissue, to include nevus lipomatosus superficialis, fibrous hamartoma of infancy, neuromuscular choristoma, fetal rhabdomyoma, and rhabdomyosarcoma.

show abstract

Rhabdomyomatous Mesenchymal Hamartoma Presenting as a Midline Mass on a Chin

Cited by 13 publications

References 11 publications

Smooth muscle hamartoma and striated muscle hamartoma: Clinicopathologic characterization of two rare entities and literature review

Smooth muscle hamartoma and striated muscle hamartoma: Clinicopathologic characterization of two rare entities and literature review

Congenital midline cervical cleft: An easily misdiagnosed disease

Rhabdomyomatous mesenchymal hamartoma presenting as a chin nodule in a 15‐year‐old male

Contact Info

Product

Resources

About